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Eosinophilic granuloma of bone: Diagnosis and management

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Abstract

Fifty patients with eosinophilic granuloma of bone were reviewed. Thirty-one lesions were in the head and neck, 24 in the extremities, seven in the pelvis, and five in the ribs. The lesions were lytic with ill-defined margins, endosteal erosion, and solid periosteal reaction. The diagnoses were obtained by surgical biopsy in 36 patients and by percutaneous biopsy in 14. Twenty-six lesions were treated with radiotherapy, 14 by surgery, and nine by surgery and radiotherapy. The last 14 cases have been treated by percutaneous injection of methylprednisolone sodium succinate into the lesion. Healing was obtained in every lesion. There were no complications.

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Authors and Affiliations

  1. Department of Diagnostic Radiology, The University of Texas, M.D. Anderson Hospital and Tumor Institute, 06810, Houston, Texas, USA

    Craig Nauert M.D., Jesus Zornoza M.D. & Thomas S. Harle M.D.

  2. Department of Pathology, The University of Texas, M.D. Anderson Hospital and Tumor Institute, Houston, Texas, USA

    Alberto Ayala M.D.

Authors
  1. Craig Nauert M.D.
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  2. Jesus Zornoza M.D.
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  3. Alberto Ayala M.D.
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  4. Thomas S. Harle M.D.
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Nauert, C., Zornoza, J., Ayala, A. et al. Eosinophilic granuloma of bone: Diagnosis and management. Skeletal Radiol 10, 227–235 (1983). https://doi.org/10.1007/BF00357895

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