Abstract
Avian- and mammalian-haemoglobin synthesis show different sensitivities to elevated temperatures. Temperature-dependent, reversible polyribosome disaggregation in avian cells occurs only at 45°C, which is 3° higher than the temperature for mammalian cells, and seems to be due to a block in the initiation of new polypeptide chains. The implications of these findings are discussed.
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References
SpirinA. S., in A. A.Moscona and A.Monroy (eds.), Current Topics in Developmental Biology, Academic Press, New York, 1966, p. 1.
TomkinsG. M., GelehrterT. D., GrannerD., MartinJr.D., SamuelsH. H., and ThompsonE. B., Science 166, 1474 (1969).
FanH. and PenmanS., J. Mol. Biol. 50, 655 (1970).
TermanS. A., Proc. Nat. Acad. Sci U.S.A. 65, 985 (1970).
LodishH. F., J. Biol. Chem. 246, 7131 (1971).
LeibowitzR. and PenmanS., J. Virology 8, 661 (1971).
PerlmanS., HirschM., and PenmanS., Nature New Biol. 238, 143 (1972).
GoldsteinE. S. and PenmanS., J. Mol. Biol. 80, 243 (1973).
RudlandP. S., Proc. Nat. Acad. Sci. U.S.A. 71, 750 (1974).
HeywoodS. M., KennedyD. S., and BesterA. J., Proc. Nat. Acad. Sci. U.S.A. 71, 2428 (1974).
McCormickW. and PenmanS., J. Mol. Biol. 39, 315 (1969).
SchochetmanG. and PerryR. P., J. Mol. Biol. 63, 577 (1972).
ScherrerK. and MarcaudL., J. Cell. Physiol. 72 (Suppl. 1), 181 (1968).
Scherrer, K.: in E. Diczfalusy (ed.), Protein Synthesis in Reproductive Tissue, Sixth Karolinska Symposium on Research Methods in Reproductive Endocrinology, Bogtrykkeriet Forum, Copenhagen, p. 95.
MorelC., KayibandaB., and ScherrerK., FEBS Letters 18, 84 (1971).
MorelC., GanderE., HerzbergM., DubochetJ., and ScherrerK., Eur. J. Biochem. 36, 455 (1973).
DubochetJ., MorelC., LebleuB., and HerzbergM., Eur. J. Biochem. 36, 465 (1973).
GanderE. S., StewartA. G., MorelC., and ScherrerK., Eur. J. Biochem. 38, 443 (1973).
GordonM. S., in Animal Physiology: Principles and Adaptations, The Macmillan Company, New York, second edition, 1972, p. 353.
ScherrerK., MarcaudL., ZajdelaF., BreckenridgeB., and GrosF., Bull. Soc. Chim. Biol. 48, 1037 (1966).
Lingrel, J. B., in J. A. Last and A. I. Laskin (eds.), Methods in Molecular Biology, Marcel Dekker, Inc., New York, Vol. 2, p. 231.
SprechmanL. M. and IngramV. M., J. Biol. Chem. 247, 5004 (1972).
TerroineE. F. and TrautmannS., Ann. Physiol. Physicochim. Biol. 3, 422 (1927). Cited by Hart, J. S., in G. C. Whittow (ed.), Comparative Physiology of Thermoregulation, Academic Press, New York and London, 1971, p. 29, Table II.
SimpsonS. and GalbraithJ. J., J. Physiol. (London) 33, 225 (1905). Cited by King, J. R. and Farner, D. S., in A. J. Marshall (ed.), Biology and Comparative Physiology of Birds, Academic Press, New York and London, 1961, p. 277, Table X.
StewartA. G., GanderE. S., MorelC., LuppisB., and ScherrerK., Eur. J. Biochem. 34, 205 (1973).
SchreierM. H., StaehelinT., StewartA., GanderE., and ScherrerK., Eur. J. Biochem. 34, 213 (1973).
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Viscardi, R.C., Ozaki, L.S. & Morel, C. Different sensitivities of avian- and mammalian-haemoglobin synthesis to elevated temperatures. Molecular Biology Reports 2, 41–47 (1975). https://doi.org/10.1007/BF00357296
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DOI: https://doi.org/10.1007/BF00357296