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A novel partial t haplotype with a Brachyury-independent effect on tail phenotype

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Abstract

The btm (brachyury-interacting tail length modifier) mutation was discovered in strain MOL-NIS derived from Japanese wild mice (Mus musculus molossinus) as an autosomal recessive mutation. Homozygotes for this mutation show a short tail phenotype and, moreover, this mutation causes the tailless character by interacting with the T (brachyury) gene on Chromosome (Chr) 17. Our linkage tests and RFLP analyses suggest that btm is located within the t complex on Chr 17 and represents a new partial t haplotype.

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Fujimoto, A., Wakasugi, N. & Tomita, T. A novel partial t haplotype with a Brachyury-independent effect on tail phenotype. Mammalian Genome 6, 396–400 (1995). https://doi.org/10.1007/BF00355639

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  • DOI: https://doi.org/10.1007/BF00355639

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