Abstract
This is the first known attempt to quantitate periosteal resorption (PR) and perisoteal neostosis (PN) by a semi-automatic image analysis system (Zeiss MOP-3). The normal ranges and errors for PR were found to be similar to those of a previous study using a measuring magnifier. The findings in chronic renal failure patients showed that MOP-3 measurements were actually diagnostically slightly less sensitive than the results by a simple grading method. Comparison with plasmaimmunoreactive parathyroid hormone (iPTH) concentrations showed that while the latter had a higher sensitivity for detection of hyperparathyroidism, the radiologic parameters nevertheless showed abnormal PR in 12% of the observations where iPTH was normal. Both PR and PN correlated significantly with iPTH (r=0.55 and 0.30 respectively, P<0.01).
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Meema, H.E., Oreopoulos, D.G. & Murray, T.M. Periosteal resorption and periosteal neostosis: Comparison of normal subjects and renal failure patients on chronic ambulatory peritoneal dialysis using MOP-3 image analysis system and a grading method. Skeletal Radiol 15, 14–20 (1986). https://doi.org/10.1007/BF00355067
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DOI: https://doi.org/10.1007/BF00355067