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References
Barrett, J.C., Anderson, M. (1993). Molecular mechanisms of carcinogenesis in human and rodents. Mol. Carcinog. 7, 1–13.
Jacob, H.J., Brown, D.M., Bunker, R.K., Daly, M.J., Dau, V.J., Goodman, A., Koike, G., Kren, V., Kurtz, T., Lernmark, A., Levan, G., Mao, Y., Pettersson, A., Pravenec, M., Simon, J.S., Szpirer, C., Szpirer, J., Trolliet, M.R., Winer, E.S., Lander, E.S. (1995). A genetic linkage map of the laboratory rat, Rattus norvegicus. Nature Genet. 9, 63–69.
Joslyn, G., Carlson, M., Thliveris, A., Albertsen, H., Gelbert, L., Samowitz, W., Groden, J., Stevens, J., Spirio, L., Robertson, M., Sargeant, L. Krapcho, K., Wolff, E., Burt, R., Hughes, J.P., Warrington, J., McPherson, J., Wasmuth, J., Le Paslier, D., Abderrahim, H., Cohen, D., Leppert, M., White, R., (1991). Identification of deletion mutations and three new genes at the familial polyposis locus. Cell 66, 601–613.
Kakiuchi, H., Watanabe, M., Ushijima, T., Toyota, M., Imai, K., Weisburger, J.H., Sugimura, T., Nagao, M. (1995). Specific 5′-GGGA-3′ to 5′-GGA-3′ mutation of the APC gene in rat colon tumors induced by 2-amino-l-methyl-6-phenylimiazo[4,5-bpyridine. Proc. Natl. Acad. Sci. USA 94, 910–914.
Kinzler, K.W., Nilbert, M.C., Su, L.-K., Vogelstein, B., Bryan, T.M., Levy, D.B., Smith, K.J., Preisinger, A.C., Hedge, P., McKechnie, D., Finniear, R., Markham, A., Groffen, J., Bouski, M.S., Altschul, S.F., Horii, A., Ando, H., Miyoshi, Y., Miki, Y., Nishisho, I., Nakamura, Y., (1991). Identification of FAP locus gene from chromosome 5q21. Science 253, 661–665.
Lander, E., Green, P. (1987). Construction of multiple genetic maps in humans. Proc. Natl. Acad. Sci. USA 84, 2363–2367.
Luongo, C., Gould, K.A., Su, L.-K., Kinzler, K.W., Vogelstein, B., Dietrich, W., Lander, E.S., Moser, A.R. (1993). Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse. Genomics 15, 3–8.
Miyoshi, Y., Ando, H., Nagase, H., Nishisho, I., Horii, A., Miki, Y., Mori, T., Utsunomiya, J., Baba, S., Petersen, G., Hamilton, S.R., Kinzler, K.W., Vogelstein, B., Nakamura, Y. (1992a). Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients. Proc. Natl. Acad. Sci. USA 89, 4452–4456.
Miyoshi, Y., Nagase, H., Ando, H., Horii, A., Ichii, S., Nakatsuru, S., Aoki, T., Miki, Y., Mori, T., Nakamura, Y. (1992b). Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum. Mol. Genet. 1, 229–233.
Oshima, M., Sugiyama, H., Kitagawa, K., Taketo, M. (1993). APC gene messenger RNA: novel isoforms that lack exon 7. Cancer Res 53, 5589–5591.
Powell, S.M., Petersen, G., Krush, A.J., Booker, S., Jen, J., Giardiello, F.M. Hamilton, S.R., Vogelstein, B., Kinzler, K.R. (1992). Mittations occur early during coloretal tumorigenesis. Nature 359, 235–237.
Rubinfeld, B., Souza, B., Albert, I., Muller, O., Chamberlain, S.H., Masiarz, F.R., Munemitsu, S., Polakis, P. (1993). Association of the APC gene product with β-catenin. Science 262, 1731–1734.
Serikawa, T., Kuramoto, T., Hilbert, P., Mori, M., Yamada, J., Dubay, C.J., Lindpainter, K., Ganten, D., Guenet, J.-L., Lathrop, M., Beckmann, J.S. (1992). Rat gene mapping using PCR-analyzed microsatellites. Genetics 131, 703–723.
Su, L.-K., Vogelstein, B., Kinzler, K.W. (1993). Association of the APC tumor suppressor protein with catenins. Science 262, 1734–1737.
van Kessel, A.G., Straub, R.E., Silverman, G.A., Overhauser, J. (1994). Report of the second international workshop on human chromosome 18 mapping. Cytogent. Cell Genet. 65, 142–155.
Yamada, J., Kuramoto, T., Serikawa, T. (1994). A rat genetic linkage map and comparative maps for mouse or human homologous rat genes. Mamm Genome 5, 63–83.
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The nucleotide sequence data reported in this paper will appear in the GSDB, DDBJ, EMBL, and NCBI nucleotide sequence databases with the accession number D38629.
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Toyota, M., Ushijima, T., Kakiuchi, H. et al. cDNA cloning of the rat APC gene and assignment to Chromosome 18. Mammalian Genome 6, 746–748 (1995). https://doi.org/10.1007/BF00354300
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DOI: https://doi.org/10.1007/BF00354300