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Chromosomal localizations of mouse Fgf2 and Fgf5 genes

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Abstract

The mouse Fgf2 and Fgf5 genes, two members of the FGF family whose human homologs are on the long arm of chromosome (chr) 4, were localized by using in situ chromosomal hybridization, to mouse Chrs 3 and 5, respectively.

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References

  • Adelaïde, J., Matteï, M.G., Marics, I., Raybaud, F., Planche, J., deLapeyriere, O., and Birnbaum, D.: Chromosomal localization of the hst oncogene and its co-amplification with the int.2 oncogene in a human melanoma. Oncogene 2: 413–416, 1988.

    Google Scholar 

  • Casey, G., Smith, R., McGillivray, D., Peters, G., and Dickson, C.: Characterization and chromosome assignment of the human homolog of int-2, a potential proto-oncogene. Mol Cell Biol 6: 502–510, 1986.

    Google Scholar 

  • Cox, R., Copeland, N., Jenkins, N., and Lehrach, H.: Interspersed repetitive element polymerase chain reaction product mapping using a mouse interspecific backcross. Genomics 10: 375–384, 1991.

    Google Scholar 

  • Davisson, M., Lalley, P., Peters, J., Doolittle, D., Hillyard, A., and Searle, A.: Report of the comparative subcommittee for human and mouse homologies. Cytogenet Cell Genet 55: 434–456, 1990.

    Google Scholar 

  • deLapeyriere, O., Rosnet, O., Benharroch, D., Raybaud, F., Marchetto, S., Planche, J., Galland, F., Matteï, M.G., Copeland, N., Jenkins, N., Coulier, F., and Birnbaum, D.: Structure, chromosome mapping and expression of the murine Fgf-6 gene. Oncogene 5: 823–831, 1990.

    Google Scholar 

  • Dickson, C., Smith, R., Brookes, S., and Peters, G.: Tumorigenesis by mouse mammary tumor virus: Proviral activation of a cellular gene in the common integration region int-2. Cell 37: 529–536, 1984.

    Google Scholar 

  • Goldfarb, M.: The fibroblast growth factor family. Cell Growth Differ 1: 439–445, 1990.

    Google Scholar 

  • Haub, O., Drucker, B., and Goldfarb, M.: Expression of the murine fibroblast growth factor 5 gene in the adult central nervous system. Proc Natl Acad Sci USA 87: 8022–8026, 1990.

    Google Scholar 

  • Jaye, M., Howk, R., Burgess, W., Ricca, G., Chiu, I.M., Ravera, M., O'Brien, S., Modi, W., Maciag, T., and Drohan, W.: Human endothelial cell growth factor: Cloning, nucleotide sequence, and chromosome localization. Science 233: 541–544, 1986.

    Google Scholar 

  • Lafage-Pochitaloff, M., Galland, F., Simonetti, J., Prats, H., Matteï, M.G., and Birnbaum, D.: The human basic fibroblast growth factor gene is located on the long arm of chromsome 4 at bands q26–q27. Oncogene Res 5: 241–244, 1990.

    Google Scholar 

  • Lyon, M. and Kirby, M.: Mouse chromosome atlas. Mouse News Lett 87: 31–33, 1990.

    Google Scholar 

  • Marics, I., Adelaïde, J., Raybaud, F., Matteï, M.G., Coulier, F., Planche, J., deLapeyriere, O., and Birnbaum, D.: Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family. Oncogene 4: 335–340, 1989.

    Google Scholar 

  • Matteï, M.G., Philip, N., Passage, E., Moisan, J.P., Mandel, J.L., and Matteï, J.F.: DNA probe localization at 18p113 band by in situ hybridization and identification of a small supernumerary chromosome. Human Genet 69: 268–271, 1985.

    Google Scholar 

  • Nadeau, J.: Maps of linkage and synteny homologies between mouse and man. Trends Genet 5: 82–86, 1989.

    Google Scholar 

  • Nguyen, C., Roux, D., Matteï, M.G., deLapeyriere, O., Goldfarb, M., Birnbaum, D., and Jordan, B.: The FGF-related oncogenes hst and int.2, and the bcl.1 locus are contained within one megabase in band q13 of chromosome 11, while the fgf.5 oncogene maps to 4q21. Oncogene 3: 703–708, 1988.

    Google Scholar 

  • Peters, G., Brookes, S., Smith, R., Placzek, M., and Dickson, C.: The mouse homolog of the hstlk-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors. Proc Natl Acad Sci USA 86: 5678–5682, 1989.

    Google Scholar 

  • Peters, G., Kozak, C., and Dickson, C.: Mouse mammary tumor virus integration regions int-1 and int-2 map on different mouse chromosomes. Mol Cell Biol 4: 375–378, 1984.

    Google Scholar 

  • Prats, H., Kaghad, M., Prats, A.C., Klagsbrun, M., Lélias, J.M., Liauzun, P., Chalon, P., Tauber, J.P., Amalric, F., Smith, J., and Caput, D.: High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons. Proc Natl Acad Sci USA 86: 1836–1840, 1989.

    Google Scholar 

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Mattei, MG., Pébusque, MJ. & Birnbaum, D. Chromosomal localizations of mouse Fgf2 and Fgf5 genes. Mammalian Genome 2, 135–137 (1992). https://doi.org/10.1007/BF00353862

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  • DOI: https://doi.org/10.1007/BF00353862

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