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Rarity of squamous cell carcinoma of the thyroid: Autopsy review

  • International Association of Endocrine Surgeons—Manuscripts Presented at the 35th World Congress of the International Society of Surgery, Hong Kong, August 1993
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Abstract

Squamous cell carcinoma (SCC) of the thyroid is thought to be rare. However, SCC not infrequently occurs in conjunction with other histologic types of tumor. We reviewed 67 thyroid cancer autopsy cases obtained from two institutions from 1969 to 1981 and from 1975 to 1992, respectively. SCC was found in 19 cases (28.4%): 2 SCCs as the only malignancy and of uniform histologic type, 9 cases of tumors mixed with papillary carcinoma, and 8 cases of SCC mixed with papillary and anaplastic carcinomas. In only four of these cases was the SCC component found in the surgical specimens. These results indicate that the presence of SCC component is more likely to be found at the later stage of the disease.

Résumé

Le cancer épithélial (CE) de la thyroïde est extrêmement rare. Cependant, le CE associé à d'autres types histologiques de tumeur se voit plus souvent. Nous avons analysé 67 cas de cancer de la thyroïde provenant des autopsies de deux institutions entre respectivement, 1969 et 1981 et 1975 et 1992. Il y avait 19 cas de CE (28.4%). Parmi ceux-ci, le CE était la seule tumeur maligne et était de type histologique uniforme dans deux cas. Il y avait neuf cas de CE et de cancer papillaire, et 8 cas de CE associé à un cancer papillaire et anaplasique. Le composant CE, cependant, n'a été retrouvé sur la pièce opératoire que dans quatre cas. Ces résultats indiquent qu'il est probable que le composant CE se révèle à un stade plus tardif de l'évolution.

Resumen

El carcinoma escamocelular (CEC) de la glándula tiroides es considerado como un tumor extremadamente raro. Sin embargo, el CEC coincidente con tumores de otros tipos histológicos no es infrecuente.

Revisamos 67 autopsias de cáncer tiroidea practicadas en dos instituciones entre 1969 y 1981 y entre 1975 y 1992, respectivamente. Se halló CEC en 19 casos (28.4%): en 2 el CEC apareció como el único neoplasma maligno y con un tipo histológico uniforme, en 9 casos mezclado con carcinoma papilar y en 8 mezclado con carcinomas papilar y anaplásico.

En sólo 4 de estos casos se encontró el componente de CEC en los especímenes quirúrgicos. Tales resultados indican que la presencia del componente CEC es más probable que sea hillado en las etapas tardías de la enfermedad.

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Harada, T., Shimaoka, K., Katagiri, M. et al. Rarity of squamous cell carcinoma of the thyroid: Autopsy review. World J. Surg. 18, 542–546 (1994). https://doi.org/10.1007/BF00353760

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