Abstract
The interleukin 2 receptor (IL2RA), a human Chromosome (Chr) 10p locus, was mapped to sheep Chr 13q12-q15 by in situ hybridization. Two loci from human Chr 10q, cytochrome P450 subfamily XVII (CYP17) and the tachykinin 2 receptor (TAC2R), were assigned to sheep Chrs 22q21-q23 and 25q14-q23 respectively. The assignment of IL2RA allows the provisional assignment of the previously unassigned sheep syntenic group U15 to sheep Chr 13. Sheep linkage group 5 is predicted to be located on sheep Chr 25 on the basis of the TAC2R assignment.
This is a preview of subscription content, log in via an institution to check access.
References
Ansari, H.A., Pearce, P.D., Maher, D.W., Malcolm, A.A., Broad, T.E. (1993a). Resolving ambiguities in the karyotype of the domestic sheep (Ovis aries). Chromosoma 102, 340–347.
Ansari, H.A., Pearce, P.D., Maher, D.W. (1993b). Assignment of anchored reference loci to sheep chromosomes. Proc. 8th North American Colloquium on Domestic Animal. Cytogentics and Gene Mapping. Guelph, July 13–16, pp 59–61.
Ansari, H.A., Pearce, P.D., Maher, D.W., Malcolm, A.A., Wood, N.J., Phua, S.H., Broad, T.E. (1994a). Regional mapping of loci from human chromosome 2q to sheep chromosome 2q. Genomics 20, 122–124.
Ansari, H.A., Bosma, A.A., Bunch, T.D., Long, S.E., Popescu, C.P. (1994b). Clarification of chromosome nomenclature in the sheep (Ovis aries). Report of the committee for the standardization of the sheep karyotype. Cytogenet. Cell Genet. 67, 114–115.
Ansari, H.A., Pearce, P.D., Maher, D.W., Broad, T.E. (1994c). Regional assignment of conserved reference loci anchors unassigned linkage and syntenic groups to ovine chromosomes. Genomics, in press.
Crawford, A.M., Montgomery, G.W., Pierson, C.A., Brown, T., Dodds, K.G., Sunden, S.L.F., Henry, H.M., Ede, A.J., Swarbrick, P.A., Berryman, T., Penty, J.M., Hill, D.F. (1994). Sheep linkage mapping: nineteen linkage groups derived from the analyis of paternal half-sib families. Genetics 137, 573–579.
Echard, G., Broad, T.E., Hill, D., Pearce, P. (1994). Present status of the ovine gene map (Ovis aries): comparison with the bovine map. Mamm. Genome 5, 324–332.
Ewen, W.J., Griffiths, R.C., Ethier, S.N., Wilcox, S.A., Graves, J.A.M. (1992). Statistical analysis of in situ hybridization data: derivation and use of the Zmax test. Genomics 12, 675–682.
Ford, C.E., Pollock, D.L., Gustavsson, I. (1980). Proceedings of the First International Conference for the Standardisation of Banded Karyotypes of Domestic Animals. Heriditas 92, 145–162.
Fries, R., Eggen, A., Womack, J.E. (1993). The bovine gene map. Mamm. Genome 4, 405–428.
Gallagher, D.S., Ryan, A.M., Liou, L.S., Sastry, K.S., Womack, J.E. (1993). Somatic cell mapping of conglutinin (CGN1) to cattle syntenic group U29 and fluorescence in situ hybridization localization to chromosome 28. Mamm. Genome 4, 716–719.
Gunawardana, A. (1991). Physical mapping of polymorphic DNA markers in the Bovidae family. (A comparative study in cattle, sheep and goat.) Ph.D. Dissertation, ETH No. 9556, Swiss Federal Institute of Technology, Zurich.
Hayes, H.C., Popescu, P., Dutrillaux, B. (1993). Comparative gene mapping of lactoperoxidase, retinoblastoma, and α-lactalbumin genes in cattle, sheep and goats. Mamm. Genome 4, 593–597.
Hediger, R., Ansari, H.A., Stranzinger, G.F. (1991). Chromosome banding and gene localizations support extensive conservation of chromosome structure between sheep and cattle. Cytogenet. Cell Genet. 57, 127–134.
ISCNDA 1989. (1990). International System for Cytogenetic Nomenclature of Domestic Animals, 1989. Di Beradino, D., Hayes, H., Fries, R., Long, S. (eds). Cytogenet. Cell Genet. 53, 65–79.
Lin, C.C., Draper, P.N., De Braekeleer, M. (1985). High resolution chromosomal localization of the β-globin gene complex by in situ hybridization. Cytogenet. Cell Genet. 39, 269–274.
Masu, Y., Nakayama, K., Tamaki, H., Harada, Y., Kuno, M., Nakanishi, S. (1987). cDNA cloning of bovine substance-K receptor through oocyte expression sytem. Nature 329, 836–838.
Montgomery, G.W., Lord, E.A., Penty, J.M., Dodds, K.G., Broad, T.E., Cambridge, L.M., Sunden, S.L.F., Stone, R.T., Crawford, A.M. (1994). The Booroola fecundity (FecB) gene maps to sheep chromosome 6. Genomics 22, 148–153.
O'Brien, S.J., Womack, J.E., Lyons, L.A., Moore, K.J., Jenkins, N.A., Copeland, N.G. (1993). Anchored reference loci for comparative genome mapping in mammals. Nature Genet. 4, 103–112.
Saidi-Mehtar, N., Hors-Cayla, M-C., Van Cong, N. (1981). Sheep gene mapping by somatic cell hybridization: four syntenic groups: ENO1-PGD, ME1-PGM3, LDHB-PEPB-TPI and G6PD-PGK-GALA. Cytogenet. Cell Genet. 30, 193–204.
Saidi-Mehtar, N., Imam-Ghali, M., Heuertz, S., Hors-Cayla, M-C. (1991). Sheep gene mapping by somatic cell hybridization. Genet. Sel. Evol. 23 (Suppl. 1), 196s-200s.
Threadgill, D.S., Womack, J.E. (1991). Mapping HSA10 homologous loci in cattle. Cytogenet. Cell Genet. 57, 123–126.
Weinberg, A.D., Shaw, J., Paetkau, V., Bleackley, R.C., Magnuson, N.S., Reeves, R., Magnuson, J.A. (1988). Cloning of cDNA for the bovine IL-2 receptor (bovine Tac antigen). Immunology 63, 603–610.
Womack, J.E. (1990). Gene mapping in the cow. Adv. Vet. Sci. Comp. Med. 34, 251–271.
Zuber, M.X., John, M.E., Okamura, T., Simpson, E.R., Waterman, M.R. (1986). Bovine adrenocortical cytochrome P-45017α: regulation of gene expression by ACTH and elucidation of primary sequence. J. Biol. Chem. 261, 2475–2482.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ansari, H.A., Pearce, P.D., Maher, D.W. et al. Human Chromosome 10 loci map to three different sheep chromosomes. Mammalian Genome 6, 46–48 (1995). https://doi.org/10.1007/BF00350893
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00350893