Abstract
Lateral cervical spine radiographs of 23 pairs of twins were matched. There is a close similarity in the shape of the vertebrae of twins, particularly if monozygotic. It can also be shown that the degenerative changes in the cervical spines of twins follow a very similar pattern. The suggestion is made that the shape of individual vertebrae is of considerable significance in the development of the changes which are found with ageing, and that this similarity in shape explains the familial pattern of spondylosis.
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References
Becker KL (1967) The twin-study method in medicine and genetics. Postgrad Med 41:603
Brain WR (1963) Some unsolved problems of cervical spondylosis. Br Med J 1:771
Bull J et al. (1969) A possible genetic factor in cervical spondylosis. Br J Radiol 42:9
Douglas HH (1966) Ischemic heart disease in monozygotic twins. Dis Chest 49:522
Duthie RB, Townes PL (1967) The genetics of orthopaedic conditions. J Bone Joint Surg [Br] 49:229
Friedenberg ZB, et al. (1960) Degenerative disc disease of the cervical spine, clinical and roentgenographic studies. JAMA 174:375
Friedenberg ZB, Miller WT (1963) Degenerative disc disease of the cervical spine. J Bone Joint Surg [Am] 45:1171
Gesell A, Thompson H (1929) Learning and growth in identical infant twins: An experimental study by the method of co-twin control. Genet Psychol Monogr 6
Goldsmith JR (1966) The Karolinska studies of twins (editorial). Arch Environ Health 13:688
Horwitz T (1940) Degenerative lesions in the cervical portion of the spine. Ann Intern Med 65:1178
Kellgren JH, Lawrence JS (1958) Osteoarthrosis and disc degeneration in an urban population. Ann Rheum Dis 17:388
Kurshner LA (1970) Environment in monozygotic and dizygotic twins. Am J Psychiatry 126:1511
Newman HH et al. (1937) Twins: A study of heredity and environment. Chicago University Press. Chicago
Osborne RH, DeGeorge FV (1959) The genetic basis of morphological variation. Harvard University Press. Cambridge
Sidd JJ et al. (1966) Coronary artery disease in identical twins. N Engl J Med 274:55
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Palmer, P.E.S., Stadalnick, R. & Arnon, S. The genetic factor in cervical spondylosis. Skeletal Radiol 11, 178–182 (1984). https://doi.org/10.1007/BF00349491
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DOI: https://doi.org/10.1007/BF00349491