Summary
A case of severe hypoglycemic coma was studied by sequential Computed Tomographic Imaging (CT) of the brain. The CT 1) was normal in the early stage, 2) subsequently showed a low density area, which was enhanced by the contrast medium, in the cerebral cortex and the boundary zone between the major cerebral arteries, and 3) revealed marked enhancement in the entire cortical region and hypodensity in the periventricular region in the late stage. These CT findings, representing the course of neural cell damage by severe hypoglycemia, are discussed from the pathophysiological viewpoint.
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References
Kalimo H, Olsson Y (1980) Effects of severe hypoglycemia on the human brain. Acta Neurol Scand 62: 345–356
Auer RN, Kalimo H, Olsson Y, Siesjö BK (1985) The temporal evolution of hypoglycemic brain damage. Acta Neuropathol (Berl) 67: 13–24
Weil A, Liebert E, Heilbrunn G (1938) Histopathologic changes in the brain in experimental hyperinsulinism. Arch Neurol Psychiat 39: 467–481
Auer RN, Wieloch T, Olsson Y, Siesjö BK (1984) The distribution of hypoglycemic brain damage. Acta Neuropathol (Berl) 64: 177–191
Hirabayashi S, Kitahara T, Hishida T (1980) Computed tomography in perinatal hypoxic and hypoglycemic encephalopathy with emphasis on follow-up studies. J Comput Assist Tomogr 4: 451–456
Richardson ML, Kinrard RE, Gray MB (1981) CT of generalized gray matter infarction due to hypoglycemia AJNR 2: 366–367
Kaiser MC, Pettersson H, Harwood-Nash DC, Fitz CR, Chuang S (1981) Computed tomography of the brain in severe hypoglycemia. J Comput Assist Tomogr 5: 757–759
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Iwai, A., Sakamoto, T., Kinoshita, Y. et al. Computed tomographic imaging of the brain in after hypoglycemia coma. Neuroradiology 29, 398–400 (1987). https://doi.org/10.1007/BF00348923
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DOI: https://doi.org/10.1007/BF00348923