Summary
The case described presents all clinical features for the definition of the true “akinetic mutism” syndrome. The anatomical examination revealed a polymorphous glioblastoma involving the structure of the midline, and particularly the rostral region of the gyrus cinguli, corpus callosum and the septal areas.
Zusammenfassung
Der beschriebene Fall weist alle klinischen Merkmale auf, die den echten „akinetischen Mutismus“ charakterisieren. Die anatomische Untersuchung zeigt ein polymorphzelliges Glioblastom der vorderen Mittellinie, vor allem im rostralen Gebiet des Gyrus cinguli, Balken und Septum.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Amyes, E. W., Nielsen, J. M.: Clinico-pathologic study of vascular lesions of the anterior cingulate region. Bull. Los Angeles neurol. Soc. 20, 112–130 (1955)
Angelergues, R., de Ajuriaguerra, J., Hécaen, H.: Paralysie de la verticalité du regard d'origine vasculaire. Rev. neurol. 96, 301–319 (1957)
Barraquer-Bordas, L., Martin, J. J., Millasantos, J., Ishino, H., Grau-Veciana, J. M., Bacci, F.: Sur une nécrose thalamique avec méningo-épendymite subaiguë. Acta neurol. belg. 67, 7–24 (1967)
Barris, R. W., Schuman, H. R.: Bilateral anterior cingulate gyrus lesions: syndrome of the anterior cingulate gyri. Neurology (Minneap.) 3, 44–52 (1953)
Brage, D., Morea, R., Copello, A. R.: Syndrome nécrotique tegmento-thalamique avec mutisme akynétique. Rev. neurol. 104, 126–137 (1961)
Cairns, H., Oldfield, R. C., Pennybacker, J. B., Whitteridge, D.: Akinetic mutism with an epidermoid cyst of the third ventricle. Brain 64, 273–290 (1941)
Castaigne, P., Buge, A., Escourolle, R., Masson, M.: Ramollissement pédonculaire médian, tegmento-thalamique, avec ophtalmoplégie et hypersomnie. Rev. neurol. 106, 357–367 (1962)
Cravioto, J. C., Silberman, J., Feigin, I.: Clinical and pathological study of akinetic mutism. Neurology (Minneap.) 10, 10–21 (1960)
Denny-Brown, D.: The basal ganglia and their relations to disorders of movement. Oxford: University Press 1962
Façon, E., Stériade, M., Wertheim, N.: Hypersomnie prolongée engendrée par des lésions bilatérales du système activateur médial: le syndrome thrombotique de la bifurcation du tronc basilaire. Rev. neurol. 98, 117–133 (1958)
Fang, H. C. H., Palmer, J. J.: Vascular phenomena involving brain stem structures: a clinical and pathological correlation study. Neurology (Minneap.) 6, 402–419 (1956)
Faris, A. A.: Limbic system infarction. J. Neuropath. exp. Neurol. 26, 174–180 (1967)
French, J. D.: Brain lesions associated with prolonged unconsciousness. Arch. Neurol. Psychiat. (Chic.) 68, 727–740 (1952)
Haase, E., Luhan, J. A.: Protracted coma from delayed thrombosis of the basilar artery following electrical injury. Arch. Neurol. Psychiat. (Chic.) 1, 192–202 (1951)
Jellinger, K., Gerstenbrand, F., Pateisky, K.: Die protrahierte Form der posttraumatischen Encephalopathie. Nervenarzt 34, 145–159 (1963)
Kemper, T. L., Romanul, F. C.: State resembling akinetic mutism in basilar artery occlusion. Neurology (Minneap.) 17, 74–80 (1967)
Kroh, H.: O symetrycznej jednoczesnej martwicy w obu wzgorach wzrokowich i srodmozgowi. Neuropat. pol. 2, 89–95 (1964)
Lechi, A., Macchi, G.: Nécrose méso-diencéphalique au cours d'une méningo-encéphalite subaiguë. Acta neurol. belg. 67, 475–490 (1967)
Lechi, A., Macchi, G.: Le syndrome du pédicule artériel rétro-mamillaire. Acta neurol. belg. 74, 13–24 (1974)
Lhermitte, F., Gauthier, J. C., Marteau, R., Chain, F.: Troubles de la conscience et mutisme akynétique. Rev. neurol. 109, 115–131 (1963)
Manghi, E., Mironi, F., Saginario, M., Valla, S.: La sindrome del mutismo acinetico. G. Psichiat. Neuropat. 87, 239–244 (1959)
Nielsen, J. M., Jacobs, L. L.: Bilateral lesions of the anterior cingulate gyri. Report of a case. Bull. Los Angeles neurol. Soc. 16, 231–234 (1951)
Plum, F., Posner, J. B.: The diagnosis of stupor and coma. Philadelphia: Davis Pbl. 1966
Riser, M., Giraud, J., Dascol, A., Valdiguie, P.: Hémorragie mésodiencéphalique avec troubles de la conscience et coma terminal. Rev. neurol. 96, 252–256 (1957)
Segarra, J. M., Angelo, J. N.: In: Behavioral changes in cerebrovascular disease, Benton (Ed.), New York: Harper & Row Pbl. 1970
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Lechi, A., Pilleri, G. & Carreras, M. Akinetic mutism due to glioma of the midline. Arch. Psychiat. Nervenkr. 220, 1–7 (1975). https://doi.org/10.1007/BF00347992
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00347992