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The use of half-lives and associated confidence intervals in biological research

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Abstract

The advantage of presenting experimental data in terms of half-life is discussed and a simple method of calculating a half-life from experimental data is described. Two methods of determining the confidence interval associated with the estimate of half-life are given and advantages and disadvantages of each method are discussed.

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References

  • Draper, N.R. and Smith, H., 1981. Applied Regression Analysis, 2nd edn., (John Wiley, New York), 25

    Google Scholar 

  • Gallant, A.R., 1987. Nonlinear Statistical Models, (John Wiley, New York), 104–119

    Google Scholar 

  • Snedecor, G.W. and Cochran, W.G., 1980. Statistical Methods, 7th edn., (Iowa State University Press, Ames, Iowa), 153–155

    Google Scholar 

  • SAS Institute Inc., 1985. SAS User's Guide: Statistics, Version 5 Edition, (SAS Institute Inc., Cary, North Carolina)

    Google Scholar 

  • Zimmerman, J.J., Berry, W.J., Beran, G.W. and Murphy, D.P., 1989. Influence of temperature and age on the recovery of pseudorabies (Aujeszky's disease) virus from houseflies, Musca domestica. American Journal of Veterinary Research, 50 (9), 1471–1474

    Google Scholar 

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Authors and Affiliations

  1. Department of Statistics, Iowa State University, 50011, Ames, Iowa, USA

    M. Bryan, J. J. Zimmerman & W. J. Berry

  2. Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, 50011, Ames, Iowa, USA

    M. Bryan, J. J. Zimmerman & W. J. Berry

  3. Department of Entomology, Iowa State University, 50011, Ames, Iowa, USA

    M. Bryan, J. J. Zimmerman & W. J. Berry

Authors
  1. M. Bryan
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  2. J. J. Zimmerman
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  3. W. J. Berry
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Bryan, M., Zimmerman, J.J. & Berry, W.J. The use of half-lives and associated confidence intervals in biological research. Veterinary Research Communications 14, 235–240 (1990). https://doi.org/10.1007/BF00347743

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  • DOI: https://doi.org/10.1007/BF00347743

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