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Liver transplantation in patients with Budd-Chiari syndrome

  • Original Article
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Transplant International

Abstract

Patients with Budd-Chiari syndrome (obstruction of the hepatic veins) and associated hepatic insufficiency may be candidates for orthotopic liver transplantation (OLT). In our series of 405 OLT patients, 3 were transplanted due to Budd-Chiari syndrome (0.7%). The indication for liver transplantation in these patients was severe hepatic insufficiency (chronic in two and acute in the third one). Morphologic study of the obstructions revealed apparently different causes, including thrombi, membranous webs in hepatic veins, and hydatid cyst compression. The surgical technique employed in these transplantations was similar to that for other etiologies. Due to its implications for the future course of OLT, it is important to determine the exact etiology of Budd-Chiari syndrome in the pretransplant period and to treat the patients with early and long-term anticoagulant therapy to avoid syndrome recurrence.

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Authors and Affiliations

  1. Isabel Tintero no 1-3rd A, E-28005, Madrid, Spain

    R. Gomez

  2. Department of General and Digestive Surgery, Liver Transplantation Unit, University Hospital “12 de Octubre”, Carretera de Andalucia Km 5.4, E-28041, Madrid, Spain

    R. Gomez, E. Moreno, I. Gonzalez, C. Loinaz, I. Garcia, G. Trombatore, A. Chamorro & A. Cañete

  3. Department of Pathology, University Hospital “12 de Octubre”, Carretera de Andalucia Km 5.4, E-28041, Madrid, Spain

    F. Colina & H. Garcia

  4. Department of Pediatric Gastroenterology, University Hospital “12 de Octubre”, Carretera de Andalucia Km 5.4, E-28041, Madrid, Spain

    E. Medina

Authors
  1. R. Gomez
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  2. E. Moreno
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  3. F. Colina
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  4. I. Gonzalez
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  5. C. Loinaz
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  6. I. Garcia
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  7. G. Trombatore
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  8. H. Garcia
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  9. A. Chamorro
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  10. E. Medina
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  11. A. Cañete
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Gomez, R., Moreno, E., Colina, F. et al. Liver transplantation in patients with Budd-Chiari syndrome. Transpl Int 8, 312–316 (1995). https://doi.org/10.1007/BF00346886

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  • DOI: https://doi.org/10.1007/BF00346886

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