Abstract
Behçet's disease, a rare condition in central Europe but more common in Turkey where it was originally described, is characterized clinically by the presence of a diagnostic triad of oral and genital aphthous ulcers, meningitis, and relapsing iridocyclitis. Vascularlesions including arterial and venous occlusions, arterial aneurysms and varices are one of the common complications of Behçet's disease occur most commonly in the abdominal aorta, femoral arteries and pulmonary arteries. There have been only four reports of aneurysms of cerebral arteries in the literature. The authors describe a patient with Behçet's disease who suffered secondary subarachnoid hemorrhage due to a ruptured aneurysm of the anterior communicating artery 3 years after the initial diagnosis. This case report draws further attention to this rare entity in patients with Behçet's disease.
Similar content being viewed by others
References
Akoglu T, E Akoglu, H Kozakoglu, C Turgan, T Firat, S Caglar: Immunocomplexes in Behçet's disease. Studies in joint Disease. A interdisciplinary symposium. Bone and Joint Research Unit. The London Hospital, London, 1978
Altinörs N, E Senveli, N Arda, A Turker, Z Kars, N Cinar, S Özkan: Intracerebral hemorrhage and hematoma in Behçet's disease. Case Report. Neurosurgery 21 (1987) 582–583
Behçet H: Über rezidiverende Aphthöse, durch ein Virus verursachte Geschwüre am Mund, am Auge und den Genitalien. Dermatol Monatsschr 105 (1937) 1152–1157
Buge A, D Vincent, G Rancurel, H Dechy, M Dorra, C Betourne: Behçet's diseases with multiple intracranial arterial aneurysms. Rev Neurol (Paris) 143 (1987) 832–835
Chajek T, M Fainaru: Behçet's disease. Report of 41 cases and a review of the literature. Medicine 54 (1975) 179–196
Colvard DM, DM Robertson, JD O'Duffy. The ocular manifestations of Behçet's disease. Arch Ophthalmol 95 (1977) 1813–1817
Donatsky O: An immunofluorescence study on the cross-reaction between strep 2A and human oral mucosa. Scand J Dent Res 83 (1975) 111–119
Erken E, T Akoglu, H Kozakoglu: Serum amyloid A protein in Behçet's disease (abstract). 6th International Congress on Immunology Toronto, 420, 1986
Evans AD, CA Pallis, JD Spillane: Involvement of nervous system in Behçet's syndrome. Lancet 2 (1957) 349–352
Hamza M: Large artery involvement in Behçet's disease. Semin Arthritis Rheum 8 (1979) 223–260
Hoover CI, JS Greenspan: Immunochemical comparison of cell-wall antigens of various viridans streptococci including strain 2 A2+3 HOT from recurrent oral aphtous ulceration in man. Arch Oral Biol 28 (1983) 917–922
Jenkins AM, AIS Macpherson, B Nolan, E Housley: Peripheral aneurysms in Behçet's disease. Br J Surg 63 (1976) 199–202
Kaneko F, Y Takahashi, Y Muramatsu, Y Miura: Immunological studies on aphthous ulcer and erythema nodosum-like eruptions in Behçet's disease. Br J Dermatol 113 (1985) 303–312
Katoh K, K Matsunaga, Y Ishigatsubo, J Chiba, K Tani, H Kitamura, S Tani, BS Handwerger: Pathologically defined Neuro-vasculo-entero-Behçet's disease. J Rheumatol 12 (1985) 1186–1190
Kerr JS, ES Roac, SH Sinal, JM Mc Whorter: Intracranial arterial aneurysms complicating Behçet's disease. J Child Neurol 4 (1989) 147–149
Lehner T: Immuno-pathology of Behçet's syndrome. In: Lehner T, CG Barnes, (eds): Behçet's Syndrome London: Academic Press 1979
Martin DM, DC Nelm, BF Mackler, DL Peavy: Lymphoproliferative responses induced by streptococcal antigens in recurrent aphtous stomatitis and Behçet's syndrome. Clin Immunol Immunopathol 13 (1979) 146–155
Matsumoto T, T Uakusa, Y Fukuda: Vasculo-Behçet's disease. A Pathologic Study of Eight Cases. Human Pathol 22 (1991) 45–51
Mizushima Y: Chemotaxis and phagocytosis of leukocytes in Behçet's disease: an overview. In: Lehner T, Barnes CG (eds): Recent advences in Behçet's disease. Roayal Soviety of Medicine Services, 1986
Mizushima Y, T Matsuda, K Hoshi, S Ohno: Induction of Behçet's disease symptoms following dental treatment and streptococcal antigen skin test. J Rheumatol 15 (1988) 1029–1030
Mortada A, IZE Iman: Virus etiology of Behçet's syndrome. Brit J Ophtal 48 (1964) 250–254
Nagata K: Recurrent intracranial hemorrhage in Behçet's disease. J Neurol Neurosurg Psychiatry 48 (1985) 190–192
Ohno S: Clinical and immunological studies on ocular lesions en Behçet's Disease. In: Inaba G (ed.): Behçet's disease Tokyo: University of Tokyo Press 1981
Ohno S: Behçet's disease in the world. In: Lehner T, CG Barnes (eds). Recent advances in Behçet's disease. Royal Society of Medicine Services 1986
Oshima Y, T Shimuzu, R Yokohari, T Matsumoto, K Kano, T Kagami, H Nagaya: Clinical studies on Behçet's syndrome. Ann Rheum Dis 22 (1963) 36–39
Pamir MN, T Kansu, A Erbengi, T Zileli: Pailledema in Behçet's syndrome. Arch Neurol 38 (1981) 643–645
Park JH, MC Han, MA Bettmann: Arterial manifestation of Behçet's disease. AJR 143 (1984) 821–825
Rubinstein LJ, H Ulrich: Meningoencephalitis of Behçet's disease. Brain 86 (1963) 151–160
Sakane T, N Suzuki, Y Ueda, S Takade, Y Murakawa, T Hoshino, Y Niwa, T Tsunematsu. Analysis of interleukin 2 activity in patients with Behçet's — disease: ability of T cells to procedure and respond to interleukin-2. Arthritis Rheum 29 (1986) 371–378
Shimizu T: Clinicopathological studies on Behçet's disease. In: Dilsen N, M Konice, C Ovul (eds): Behçet's disease: Proceedings of an International Symposium on Behçet's disease. Excerpta Medica Amsterdam-Oxford 1979
Shimizu T, GE Ehrlich, G Inaba, K Hayaski: Behçet's disease. Semin Arthritis Rheum 8 (1979) 223–260
Shimizu T, T Ogino: Clinico-pathological studies on the intestinal lesions in Behçet's disease with special reference to entero-Behçet's syndrome. Stomach and Intestine 10 (1975) 1593–1600
Tsuji S, Y Suzuki, M Tomii, Y Matsuoka, H Kishimoto, S Irimajiri: Behçet's disease associated with multiple cerebral aneurysms and downhill esophageal varices caused by superior vena cava obstruction: A case report. Ryumachi 30 (1990) 375–381
Yamana K, K Kosuga, H Kinoshita, K Uroguchi, T Kinoshita, T Hirata, H Akashi, T Nakayama, K Ohiski: Vasculo-Behçet's disease: Immunological study of the formation of aneurysm. J Cardiovasc Surg 29 (1988) 751–755
Wolf SM, DL Schotland, LL Philips: Involvement of nervous system in Behçet's syndrome. Arch Neurol 12 (1965) 315–325
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ildan, F., Göçer, A.I., Baĝdatoĝlu, H. et al. Intracranial arterial aneurysm complicating Behçet's disease. Neurosurg. Rev. 19, 53–56 (1996). https://doi.org/10.1007/BF00346612
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00346612