Skip to main content
Log in

The effects of non-specifically activated immunity in rabbits on primary infestation with Rhipicephalus evertsi evertsi

  • Parasitology
  • Published:
Veterinary Research Communications Aims and scope Submit manuscript

Abstract

The secondary antibody response to sheep red blood cells and bovine serum albumin (BSA) was measured in rabbits infested with adult Rhipicephalus evertsi evertsi. The response was reduced (particularly for BSA) but still displayed anamnestic characteristics. Resistance against ixodid ticks associated with antibodies detected by gel diffusion and enzyme linked immunosorbent assay techniques early in the primary challenge was acquired by the immunized hosts only. This suggests that a non-specifically activated immune system enables hosts to develop rapid resistance against tick parasitism.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price includes VAT (Canada)

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Alani, A.J. and Herbert, I.V., 1987. Effect of host resistance on the feeding and reproductive performance of Haemaphysalis punctata and Ixodes ricinus ticks. Research in Veterinary Science, 42, 238–243

    Google Scholar 

  • Bailey, P.K., 1960. Notes on the rearing of Rhipicephalus appendiculatus and their infection with Theileria parva for experimental transmission. Bulletin of Epizootic Diseases for Africa, 8, 33–43

    Google Scholar 

  • Boyden, S.V., 1951. The adsorption of proteins on erythrocytes treated with tannic acid and subsequent haemagglutination by antiprotein antisera. Journal of Experimental Medicine, 93, 107–120

    Google Scholar 

  • Capstick, P.B., De Castro, J.J. and Nyindo, M., 1987. Intradermal reactions in cattle of three antigens derived from Rhipicephalus appendiculatus; antigen titration, specificity of reaction, selection and use to determine tick exposure in the field. Proceedings of the World Association for the Advancement of Veterinary Parasitology, Montreal, 12–15 August 1987, p. 19

  • George, J.E., Osburn, R.L. and Wikel, S.K., 1985. Acquisition and expression of resistance by Bos indicus and Bos indicus x Bos taurus calves to Amblyomma americanum infestation. Journal of Parasitology, 71, 174–182

    Google Scholar 

  • Gray, G.D. and Phillips, R.S., 1983. Suppression of primary and secondary antibody responses and inhibition of antigen priming during Babesia microti infections in mice. Parasite Immunology, 5, 123–134

    Google Scholar 

  • Labarthe, N.V., Remiao, J.O., Sacco, A.M. and Maia, L.C., 1985. Cross-reaction of tick salivary gland antigens in the Boophilus microplus cattle systems. Veterinary Parasitology, 17, 259–263

    Google Scholar 

  • Mongi, A.O., Capstick, P.B., Aganyo, C.A., De Castro, J.J. and Newson, R.N., 1987. The presence of antibodies in naive cattle and rabbits that react to whole tick homogenate of Rhipicephalus appendiculatus. Proceedings of the World Association for the Advancement of Veterinary Parasitology, Montreal, 12–15 August 1987, p. 16

  • Newson, R.M., 1978. The life cycle of Rhipicephalus appendiculatus on the Kenyan Coast. In: J.K.H.Wilde (ed.), Tick-borne Diseases and their Vectors, (Edinburgh University Press, Edinburgh), pp. 46–50

    Google Scholar 

  • Njau, B.C., 1989. Resistance to Rhipicephalus evertsi evertsi in immunosuppressed rabbits. Veterinary Research Communications, 13, 93–102

    Google Scholar 

  • Njau, B.C., Nyindo, M. and Mutani, A., 1986. Immunological responses and the role of the paralyzing toxin in rabbits infested with Rhipicephalus evertsi evertsi. American Journal of Tropical Medicine and Hygiene, 35, 1248–1255

    Google Scholar 

  • Njau, B.C., Nyindo, M. and Mutani, A., 1990. The interaction between the immune response of rabbits to heterologous antigens and primary infestation with Rhipicephalus evertsi evertsi. Veterinary Research Communications, 14, 113–122

    Google Scholar 

  • Ouchterlony, O., 1958. Diffusion-in gel methods for immunological analysis. Progress in Allergy, 55, 1–78

    Google Scholar 

  • Steel, R.G.D. and Torrie, J.H., 1960. Analysis of variance. Principles and Procedures of Statistics, (McGraw-Hill, New York), pp. 99–160

    Google Scholar 

  • Taussig, M.J., 1975. Antigenic competition. In: M.J.Hobart and I.McConnell (eds.), The Immune System, (Blackwell Scientific Publications, Oxford), pp. 165–178

    Google Scholar 

  • Voller, A. and SavignyDe, D., 1981. Enzyme-linked immunosorbent assay. In: R.A.Thompson (ed.), Techniques in Clinical Immunology, (Blackwell Scientific Publications, Oxford), pp. 157–169

    Google Scholar 

  • Wikel, S.K., 1985. Effects of tick infestation on the plaque-forming cell response to a thymic dependent antigen. Annals of Tropical Medicine and Parasitology, 79, 195–198

    Google Scholar 

  • Wikel, S.K. and Osburn, R.L., 1982. Immune responsiveness of the bovine host to repeated low-level infestations with Dermacentor andersoni. Annals of Tropical Medicine and Parasitology, 76, 405–414

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Njau, B.C. The effects of non-specifically activated immunity in rabbits on primary infestation with Rhipicephalus evertsi evertsi . Veterinary Research Communications 14, 123–128 (1990). https://doi.org/10.1007/BF00346552

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00346552

Keywords

Navigation