Abstract
Malignant tumors of the anterior cranial skull base are still a challenge for radical surgical treatment. Several different techniques and approaches have been developed over the years and the results, with mortality rates over 50%, are still not encouraging.
Here we present our results of an interdisciplinary, onestage, neurohino transfronto-transbasal surgical approach in twelve patients with such tumors.
The long-term survival rate in our patients is now 83% with a mean postoperative follow-up of 19.3 months. Two patients died due to early recurrencies and metastasis after 10 and 13 months after initial treatment and postoperative irradiation.
Another five patients with a follow-up of 34.2 months have had tumor recurrencies diagnosed at 19.5 months postoperatively. These patients have survived their recurrent tumor for 14.7 months.
Five patients, 41% of the whole group, have been living without evidence of tumor recurrence for between 2 and 35 months.
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Neubauer, U., Fahlbusch, R., Wigand, M.E. et al. Malignant tumors of the anterior cranial skull base. Neurosurg. Rev. 15, 187–192 (1992). https://doi.org/10.1007/BF00345929
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DOI: https://doi.org/10.1007/BF00345929