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Subacute sclerosing panencephalitis

Changes on CT scan during acute relapse

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Summary

A 19-year-old female patient presented in an acute state of akinetic mutism. Serological analysis of serum and cerebrospinal fluid demonstrated the presence of antibodies to measles virus. CT scan carried out during this acute phase of relapse demonstrated white matter enhancement affecting the cortical white matter of the frontal lobes and corpus callosum. These features indicate that active demyelination occurs during acute relapse in subacute sclerosing panencephalitis (SSPE) and suggest that immunotherapy should be considered during this acute phase.

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Authors and Affiliations

  1. Department of Medicine, Wentworth Hospital, Durban, South Africa

    G. Modi & P. Bill

  2. Department of Radiology, Wentworth Hospital, Durban, South Africa

    H. Campbell

Authors
  1. G. Modi
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  2. H. Campbell
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  3. P. Bill
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Modi, G., Campbell, H. & Bill, P. Subacute sclerosing panencephalitis. Neuroradiology 31, 433–434 (1989). https://doi.org/10.1007/BF00343870

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  • DOI: https://doi.org/10.1007/BF00343870

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