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The structural gene for F liver protein (Flp) maps to chromosome 5 of the mouse

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Abstract

The BXD and AKXL panels of recombinant inbred mouse strains have been typed for the F liver protein alloantigen. The structural gene for F liver protein gene (Flp) is placed on the distal part of chromosome 5, between the known markers Bcd-1 and Gus-s. This excludes the possibility that F liver protein is a major histocompatibility complex molecule, and in turn raises a question about the uniqueness of F and certain other proteins as purgers of self-reactivity among T but not B cells. The typed RI strains have then been used for the immunogenetic studies presented in the succeeding article.

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Authors and Affiliations

  1. Imperial Cancer Research Fund, Tumour Immunology Unit, Department of Zoology and Cell Biology, University College London, Gower Street, WC1E 6BT, London, England

    G. Winchester & N. A. Mitchison

  2. The Jackson Laboratory, 04609, Bar Harbor, ME, USA

    B. A. Taylor

Authors
  1. G. Winchester
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  2. N. A. Mitchison
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  3. B. A. Taylor
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Winchester, G., Mitchison, N.A. & Taylor, B.A. The structural gene for F liver protein (Flp) maps to chromosome 5 of the mouse. Immunogenetics 26, 356–358 (1987). https://doi.org/10.1007/BF00343704

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  • DOI: https://doi.org/10.1007/BF00343704

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