Summary
The cation content and composition of mineral deposits in cerebral vessels in a case of Fahr's syndrome were studied by laser-spectrographic analysis. It was shown that in addition to Ca and Fe, other minerals such as Mg, Al, and Zn accumulated in pathologic deposits. The occurrence of cations other than Ca and Fe in these deposits had not been previously reported. The observations made in this study may contribute to a better understanding of the etiopathogenesis of Fahr's syndrome.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Adachi, M., Wellman, K. F.: Histochemical studies on the pathogenesis of idiopathic nonarteriosclerotic cerebral calcifications. J. Neuropathol. Exp. Neurol. 27, 483–499 (1968)
Arendt, A.: Idiopathische, nicht arteriosklerotische interzerebrale Gefäßverkalkung nach Fahr. Monatsschr. Psychiat. Neurol. 24, 132–140 (1956)
Erbslöh, F., Bochnik, H.: Symmetrische Pseudokalk-und Kalkablagerungen im Gehirn. In: Handbuch der speziellen pathologischen Anatomie und Histologie (O. Lubarsch et al., ed.), 13. Band, 2. Teil, p. 1769. Berlin-Göttingen-Heidelberg: Springer 1958
Fahr, T.: Idiopathische Verkalkung der Hirngefäße. Zentralbl. Allg. Pathol. Pathol. Anat. 50, 129–141 (1930)
Guseo, A., Boldizsa'r, F., Gellert, M.: Elektronenoptische Untersuchungen bei „striatodentaler Calcifikation“ (Fahr). Acta Neuropathol. (Berl.) 31, 305–313 (1975)
Kozik, M., Arcimowicz, B., Dembczyński, J.: An attempt of applying laser rays for the detection and analysis of chemical elements in tissue slices. Acta Histochem. (Jena) 37, 203–205 (1970)
Kozik, M., Warchoł, J., Arcimowicz, B.: The assay of acid phosphatase activity by means of a laser method. Histochemie 24, 245–250 (1970)
Kozik, M.: Zastosowanie analizy laserowej w histochemii. In Handbook: Histochemiczne metody badania komórek i tkanek (A. Krygier-Stojalowska, H. G. Godlewski, eds.), pp. 149–164. Warszawa: PWN, 1975
Liber, A. F.: Chelatable iron in senile siderocalcification of the human brain. J. Neuropathol. Exp. Neurol. 24, 675–681 (1965)
Melchior, J. C., Benda, C. E., Yakovler, P. I.: Familial Idiopathic Calcification in Childhood. AMAJ Dis. Child. 99, 787–794 (1960)
Neumann, M.: Iron and calcium dysmetabolism in the brain. J. Neuropathol. Exp. Neurol. 22, 148–163 (1963)
Papierz, W.: Rozległe zwapnienia śródmózgowe O typie choroby Fahr'a. Neuropatol. Pol. 12, 77–82 (1974)
Schiffer, D.: Calcification in nervous tissue. In: Pathology of the Nervous System (I. Minckler, ed.). New York: McGraw-Hill 1971
Virchow, R.: Kalk-Metastasen. Virchows Arch. 8, 103–113 (1855)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kozik, M., Kulczycki, J. Laser-spectrographic analysis of the cation content in Fahr's syndrome. Arch. Psychiat. Nervenkr. 225, 135–142 (1978). https://doi.org/10.1007/BF00343397
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00343397