Summary
The Na+, K+, Ca2+, Mg2+, Cl−, and Pi concentrations in serum and lumbar CSF of 17 controls and 62 patients with neuromuscular diseases were determined and the values statistically evaluated. Although alterations in ion concentrations specifical to different groups were not observed in either of these biological fluids, the significant increase in serum Pi concentration in Duchenne muscular dystrophy seems to be remarkable. It is suggested that the possible alterations in the ion content of the serum and CSF may contribute additional data to the diagnosis of various neuromuscular diseases.
Zusammenfassung
Bei 62 Patienten mit neuromuskulären Erkrankungen und bei 17 Kontrollpatienten wurde die Konzentration von Na+, K+, Ca2+, Mg2+, Cl− und anorganischem Phosphor (Pi) im Serum und im lumbalen Liquor vergleichend gemessen, und die Werte wurden statistisch bearbeitet. Obwohl keine für die verschiedenen Erkrankungstypen charakteristischen Veränderungen beobachtet werden konnten, ist die signifikante Erhöhung der Pi-Konzentration im Serum bei Duchenne-Dystrophie doch erwähnenswert. Die eventuellen Veränderungen der Ionenkonzentration im Serum und im Liquor können zur Diagnosestellung bei verschiedenen neuromuskulären Erkrankungen beitragen.
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Supported by Ministry of Health, Hungary-/2-20-0303-01-0/M.
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Csenkér, É., Diószeghy, P., Fekete, I. et al. Ion concentrations in serum and cerebrospinal fluid of patients with neuromuscular diseases. Arch Psychiatr Nervenkr 231, 251–258 (1982). https://doi.org/10.1007/BF00343295
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DOI: https://doi.org/10.1007/BF00343295