Summary
An electron microscope study of the rat supraoptic nucleus, substantia nigra, neostriatum and periventricular preoptic area demonstrates that nematosomes are present within the perikaryon of neurons located in these structures. The latter structure may be found in close association with the subsynaptic web of axosomatic synapses. Numerous micro-filaments fan out from the nematosome and link the latter organelle to the ribosomes, the cytoplasmic membranes and the plasma membrane thus establishing an interwoven filamentous cytoplasmic network. A possible close relationship between the nematosomes and the neurofilaments and neurotubules is discussed.
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Akert, K., Pfenninger, K., Sandri, C.: The fine structure of synapses in the subfornical organ of the cat. Z. Zellforsch. 81, 537–556 (1967).
Akert, K., Moor, H., Pfenninger, K., Sandri, C.: Contributions of new impregnation methods and freeze etching to the problems of synaptic fine structure. In: Mechanisms of synaptic transmission (K. Akert and P. G. Waser, eds.), pp. 223–240. Amsterdam, London and New York: Elsevier Publ. Co. 1969.
Colonnier, M.: Synaptic patterns on different cell types in the different laminae of the cat visual cortex. An electron microscope study. Brain Res. 9, 268–287 (1968).
De Robertis, E.: Histophysiology of synapses and neurosecretion, pp. 27–48. Oxford, London, Edinburgh, New York, Paris and Frankfurt: Pergamon Press 1964.
Gray, E. G.: Axo-somatic and axo-dendritic synapses of the cerebral cortex: An electron microscope study. J. Anat. (Lond.) 93, 420–433 (1959).
—: Electron microscopy of presynaptic organelles of the spinal cord. J. Anat. (Lond.) 97, 101–106 (1963).
Grillo, M. A.: Cytoplasmic inclusions resembling nucleoli in sympathetic neurons of adult rats. J. Cell Biol. 45, 100–117 (1970).
Le Beux, Y. J.: An ultrastructural study of the neurosecretory cells of the medial vascular prechiasmatic gland, the preoptic recess and the anterior part of the suprachiasmatic area. I. Cytoplasmic inclusions resembling nucleoli. Z. Zellforsch. 114, 404–440 (1971).
Loos, H. Van der: Fine structure of synapses in the cerebral cortex. Z. Zellforsch. 60, 815–825 (1963).
Milhaud, M., Pappas, G. D.: Postsynaptic bodies in the habenula and interpeduncular nuclei of the cat. J. Cell Biol. 30, 437–441 (1966).
Peters, A., Palay, S. L., F. Webster, H. de: The fine structure of the nervous system. The cells and their processes, pp. 25–26 and 68–69. New York, Evanston and London: Hoeber Medical Division, Harper and Row 1970.
Schmitt, F. O.: Fibrous proteins and neuronal dynamics. In: Cellular dynamics of the neuron (S. H. Barondes, ed.), pp. 95–111. New York and London: Acad. Press 1969.
Taxi, J.: Etude de l'ultrastructure des zones synaptiques dans les ganglions sympathiques de la grenouille. C. R. Acad. Sci. (Paris) 252, 174–176 (1961).
Zucker-Franklin, D.: Microfibrils of blood platelets: their relationship to microtubules and the contractile protein. J. clin. Invest. 48, 165–175 (1969).
—: The submembraneous fibrils of human blood platelets. J. Cell Biol. 47, 293–299 (1970).
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This work was supported by research grant MA-3448 from the Medical Research Council of Canada. The skillful technical assistance of Miss Marjolaine Thiffeault is gratefully acknowledged.
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Le Beux, Y.J., Langelier, P. & Poirier, L.J. Further ultrastructural data on the cytoplasmic nucleolus resembling bodies or nematosomes. Their relationship with the subsynaptic web and a cytoplasmic filamentous network. Z. Zellforsch. 118, 147–155 (1971). https://doi.org/10.1007/BF00341559
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DOI: https://doi.org/10.1007/BF00341559