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Outcome of perianal fistulae in Crohn's disease —value of Hughes' pathogenic classification

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Abstract

Applying the Hughes' pathogenic classification of anoperineal lesions of Crohn's disease, this study was conducted to find out its possible prognostic value in perianal fistulas. Thirty-eight patients with ano-perianal fistulas were included; primary specific lesions (condyloma, cavitating ulcer, fissure) were found in 22 patients (group 1) and were absent in the other 16 patients (group 2). Patients of group 1 underwent more abdominal surgical interventions (G1: 68%; G2: 31%-P=0.05), as well as proctological interventions (G1: 2.95 operations/patient vs 1.35 in G2-P=0.01). Perfect continence was recorded ultimately in 31.8% patients of G1 compared to 62.5% of G2. This study shows the very poor prognosis of ano-perianal fistulas in Crohn's disease.

Résumé

Utilisant le classification pathogénique de Hughes des lésions périanales de la maladie de Crohn, cette étude a été menée pour trouver sa possible valeur pronostique dans les fistules péri-anales. 38 malades avec des fistules péri-anales ont été étudiés des lésions spécifiques primaires (condylome, ulcère creusant, fissure) ont été trouvées chez 22 patients (groupe 1) et étaient absentes chez 16 autres patients (groupe 2). Les patients du groupe 1 subirent plus d'interventions chirurgicales abdominales (G1: 68%, G2: 31%-P=0.05) aussi bien que d'interventions proctologiques (G1:22,95 opérations/patients vs 1,35 dans le G2-P=0.01). La continence parfaite a été trouvée à la fin chez 31,8% des patients du groupe 1 contre 62,5% du groupe 2. Cette étude montre le très mauvais pronostic des fistules péri-anales dans la maladie de Crohn.

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Abbreviations

TPN:

total parenteral nutrition

G1:

group 1

G2:

group 2

References

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François, Y., Vignal, J. & Descos, L. Outcome of perianal fistulae in Crohn's disease —value of Hughes' pathogenic classification. Int J Colorect Dis 8, 39–41 (1993). https://doi.org/10.1007/BF00341275

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  • DOI: https://doi.org/10.1007/BF00341275

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