Skip to main content
SpringerLink
Log in

The fine structure of the trabeculum cribriforme and the inner wall of Schlemm's canal in the normal human eye

  • Published:
Zeitschrift für Zellforschung und Mikroskopische Anatomie Aims and scope Submit manuscript

Summary

The tissue in the area of the inner wall of Schlemm's canal was examined in four human eyes.

  1. 1.

    Flocculent material was found within some of the giant cytoplasmic vacuoles of the Schlemm canal endothelium.

  2. 2.

    In a few cases, gaps were seen in the endothelial lining of the inner wall. In each case, a non-endothelial cell was interposed in the gap.

  3. 3.

    Collagen fibrils with regular periodicity was found immediately beneath the inner wall endothelium.

  4. 4.

    Erythrocytes were observed in the cribriform area among the extracellular tissue components.

  5. 5.

    The extracellular compartment of the cribriform area is continuous with the cores of the corneoscleral trabeculae.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Farquhar, M. G., and G. E. Palade: Junctional complexes in various epithelia. J. Cell Biol. 17, 375–412 (1963).

    Google Scholar 

  • Fawcett, D. W.: The cell. Philadelphia and London: W. B. Saunders Co. 1966.

    Google Scholar 

  • Feeney, L., and S. Wissig: Contributions of electron microscopy to the understanding of the production and outflow of aqueous humour. Outflow studies using an electron dense tracer. Trans. Amer. Acad. Ophthal. Otolaryng. In press.

  • Flocks, M.: The anatomy of the trabecular meshwork as seen in tangential section. Arch. Ophthal. 56, 708–718 (1956).

    Google Scholar 

  • Garron, L. K., and M. L. Feeney: Electron microscopic studies of the human eye. II. Study of the trabeculae by light and electron microscopy. Arch. Ophthal. 62, 966–973, 1067–1076 (1959).

    Google Scholar 

  • Holmberg, Å.: The fine structure of the inner wall of Schlemm's canal. Arch. Ophthal. 62, 956–958, 1047–1056 (1959).

    Google Scholar 

  • —: Schlemm's canal and the trabecular meshwork. An electron microscopic study of the normal structure in man and monkey (Cercopithecus ethiops). Docum. ophthal. (Den Haag) 19, 339–373 (1965).

    Google Scholar 

  • Hørven, I.: A radioautographic study of erythrocyte resorption from the anterior chamber of the human eye. Acta ophthal. (Kbh.) 42, 600–608 (1964).

    Google Scholar 

  • Iwamoto, T.: Light and electron microscopy of the presumed elastic components of the trabeculae and scleral spur of the human eye. Invest. Ophthal. 3, 144–156 (1964).

    Google Scholar 

  • Petris, S. de, G. Karlsbad, and B. Pernis: Filamentous structures in the cytoplasm of normal mononuclear phagocytes. J. Ultrastruct. Res. 7, 39–55 (1962).

    Google Scholar 

  • Reynolds, E. S.: The use of lead citrate at high pH as an electron opaque stain in electron microscopy. J. Cell Biol. 17, 208–211 (1963).

    Google Scholar 

  • Rohen, J. W.: Das Auge und seine Hilfsorgane. In: Handbuch der mikroskopischen Anatomie des Menschen, Bd. III/4. Berlin-Göttingen-Heidelberg: Springer 1964.

    Google Scholar 

  • —: Über die reaktiven Veränderungen des Trabeculum corneosclerale im Primatenauge nach Einwirkung von Hyaluronidase. (Histologische und Elektronenmikroskopische Untersuchungen). Z. Zellforsch. 65, 627–645 (1965).

    Google Scholar 

  • Sondermann, R.: Beitrag zur Entwicklung und Morphologie des Schlemmschen Kanals. Albrecht v. Graefes Arch. Ophthal. 124, 521–543 (1930).

    Google Scholar 

  • —: Über Entstehung, Morphologie und Function des Schlemmschen Kanals. Acta ophthal. (Kbh.) 11, 280–301 (1933).

    Google Scholar 

  • Speakman, J. S.: Drainage channels in the trabecular wall of Schlemm's canal. Brit. J. Ophthal. 44, 513–523 (1960).

    Google Scholar 

  • —: The structure of the trabecular meshwork in relation to the pathogenesis of open angle glaucoma. Canad. med. Ass. J. 84, 1066–1074 (1961).

    Google Scholar 

  • Spelsberg, W.W., and G. B. Chapman: Fine structure of human trabeculae. Arch. Ophthal. 67, 773–784 (1962).

    Google Scholar 

  • Theobald, G. Dvorak: Schlemm's canal: Its anastomoses and anatomic relations. Trans. Amer. ophthal. Soc. 32, 574–595 (1934).

    Google Scholar 

  • —: Further studies on the canal of Schlemm. Its anastomoses and anatomic relations. Amer. J. Ophthal. 39, 65–89 (1955, April part II).

    Google Scholar 

  • Vegge, T.: Ultrastructure of normal human trabecular endothelium. Acta ophthal. (Kbh.) 41, 193–199 (1963).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Anatomical Institute, University of Oslo, Norway

    Torgeir Vegge

Authors
  1. Torgeir Vegge
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Supported in part by Grant NB 02215 from the National Institute of Neurological Diseases and Blindness, US Public Health Service.

During part of this study the author was a fellow of the Norwegian Research Council for Science and the Humanities.

The specimens for investigation were placed at the author's disposal by Prof. T. L. Thomassen, M. D., head of the Eye Clinic, Oslo University Hospital, and by J. Ytteborg, M. D., head of the Eye Department, Oslo City Hospital. This aid is gratefully acknowledged.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vegge, T. The fine structure of the trabeculum cribriforme and the inner wall of Schlemm's canal in the normal human eye. Zeitschrift für Zellforschung 77, 267–281 (1967). https://doi.org/10.1007/BF00340793

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00340793

Keywords

Search

Navigation