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The cytology of apocrine sweat glands

I. Cat and monkey

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Zeitschrift für Zellforschung und Mikroskopische Anatomie Aims and scope Submit manuscript

Summary

The apocrine sweat glands of cat and monkey have been studied by light and electron microscopy. The apocrine secretory cells of the cat are columnar cells with prominent apical cytoplasmic caps extending into the gland lumen beyond the zone of terminal bars (zonulae occludentes). Many secretory vacuoles are present in the cytoplasm, and they contain acid mucopolysaccharide demonstrable by light microscopy. These secretory vacuoles arise from prosecretory vacuoles in the region of the Golgi apparatus and are liberated from the apical cell surface as in other merocrine cells. The apocrine duct is short and the cells have scant mitochondria. The apocrine secretory cells of the monkey have secretory vacuoles similar to those of the cat but are fewer in number. The monkey apocrine cells also contain unidentified bodies similar to those seen in Langerhans cells of the epidermis. These cells liberate secretory vacuoles in a merocrine manner. “Apocrine” or “decapitation secretion” is regarded as an artifact.

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References

  • Aoki, T.: Stimulation of the sweat glands in the hairy skin of the dog by adrenalin, noradrenalin, acetyloholine, mecholyl and pilocarpine. J. invest. Derm. 24, 545–555 (1955).

    Google Scholar 

  • Bargmann, W., K. Fleischhauer u. A. Knoop: Über die Morphologie der Milchsekretion. II. Zugleich eine Kritik am Schema der Sekretionsmorphologie. Z. Zellforsch. 53, 545–568 (1961).

    Google Scholar 

  • Bauer, W.C.: Personal communication.

  • Birbeck, M.S., A.S. Breathnach, and J.D. Everall: An electron microscope study of basal melanocytes and highlevel clear cells (Langerhans cells) in vitiligo. J. invest. Derm. 37, 51–64 (1961).

    Google Scholar 

  • Breathnach, A.S.: Observations on cytoplasmic organelles in Langerhans cells of human epidermis. J. Anat. (Lond.) 98, 265–270 (1964).

    Google Scholar 

  • —, M.S.C. Birbeck, and J.D. Everall: Observations bearing on the relationship between Langerhans cells and melanocytes. Ann. N. Y. Acad. Sci. 100, 223–238 (1963).

    Google Scholar 

  • Caramia, F.: Ultrastructure of mouse submaxillary glands I. Sexual differences and II. Effect of Castration in the mole. (Subm. for publ.).

  • Charles, A.: An electron microscopic study of the human axillary apocrine gland. J. Anat. (Lond.) 93, 226–232 (1959).

    Google Scholar 

  • Dalton, A.J.: A chrome osmium fixative for electron microscopy. Anat. Rec. 121, 281 (1955).

    Google Scholar 

  • Ellis, R.A.: The fine structure of palmar eccrine sweat glands of Macaca mulatta, Anat. Rec. 136, 187 (1960).

    Google Scholar 

  • —, and W. Montagna: The sweat glands of the Lorisidae. In: Evolutionary and Genetic Biology of Primates (J. Buettner-Janusch, ed.), p. 197–228. New York: Academic Press 1963.

    Google Scholar 

  • Farquhar, M.G., and G.E. Palade: Junctional complexes in various epithelia. J. Cell Biol. 17, 375–412 (1963).

    Google Scholar 

  • Florey, H.W.: Electron microscopic observations on goblet cells of the rat colon. Quart. J. exp. Physiol. 45, 329–336 (1960).

    Google Scholar 

  • Hollmann, K.H.: L'ultrastructure de la glande mammaire normale de la souris en lactation. J. Ultrastruct. Res. 2, 423–443 (1959).

    Google Scholar 

  • Hurley, H.S., and W.B. Shelley: The human apocrine sweat gland in health and disease. Springfield: Ch.C.Thomas 1960.

    Google Scholar 

  • Ihjima, S., and T. Oono: Cytological studies of gll. vestibulares nasi of the cat after adrenalin injection. Okajimas Folia anat. jap. 31, 325–332 (1958).

    Google Scholar 

  • Kurosumi, K.: Electron microscopic analysis of the secretion mechanism. Int. Rev. Cytol. 11, 1–124 (1961).

    Google Scholar 

  • —, T. Kitamura, and T. Iijima: Electron microscopic studies on the human axillary apocrine sweat gland. Arch. Hist. Jap. 16, 523–566 (1959).

    Google Scholar 

  • Langley, L. L., and R.S. Brown: Stop-flow analysis of ionic transfer in the dog parotid gland. Amer. J. Physiol. 199, 59–62 (1960).

    Google Scholar 

  • Lillie, R.D.: Histopathologic Technic and Practical Histochemistry. New York: McGraw Hill Book Co. 1954.

    Google Scholar 

  • Luft, J.H.: Improvements in epoxy resin embedding methods. J. biophys. biochem. Cytol. 9, 409–414 (1961).

    Google Scholar 

  • Mercer, E.H., B.L. Munger, G.E. Rogers, and S.I. Roth: A suggested nomenclature for fine structural components of keratin and keratin-like products of cells. Nature (Lond.) 201, 367–368 (1963).

    Google Scholar 

  • Millonig, G.: Further observations on a phosphate buffer for osmium solutions in fixation. Fifth Internat. Congr. for Elec. Micr. 2, P-8 (1962).

  • Montagna, W.: The structure and function of skin, 2nd ed. New York: Academic Press 1962.

    Google Scholar 

  • Mowry, R.W.: Alcian blue technics for the histochemical study of acidic carbohydrates. J. Histochem. 4, 407 (1956).

    Google Scholar 

  • —: Improved procedures for the staining of acidic polysaccharides by Muller's colloidal (hydrous) ferric oxide and its combination with the Feulgen and periodic acid-Schiff reaction. Lab. Invest. 7, 566–576 (1958).

    Google Scholar 

  • Munger, B.L.: The ultrastructure and histophysiology of human eccrine sweat glands. J. biophys. biochem. Cytol. 11, 385–402 (1961a).

    Google Scholar 

  • — Staining methods applicable to sections of osmiumfixed tissue for high resolution light microscopy. J. biophys. biochem. Cytol. 11, 502–505 (1961b).

    Google Scholar 

  • — Histochemical studies on seromucous- and mucous-secreting cells of the human salivary glands. Amer. J. Anat. 115, 411–430 (1964).

    Google Scholar 

  • - The cytology of apocrine sweat glands II. Human. Z. Zellforsch. (in press) (1965).

  • —, and S.W. Brusilow: An electron microscopic study of eccrine sweat glands of the cat foot and toe pads. Evidence for ductal reabsorption in the human. J. biophys. biochem. Cytol. 11, 403–417 (1961).

    Google Scholar 

  • Palay, S.L.: The Morphology of Secretion. In: Frontiers in Cytology (S.L. Palay, Ed.). New Haven: Yale University Press 1958.

    Google Scholar 

  • Parks, H.F.: Morphological study of the extrusion of secretory materials by the parotid glands of mouse and rat. J. Ultrastruc. Res. 6, 449–465 (1962).

    Google Scholar 

  • Pearse, A.G.E.: Histochemistry, Theoretical and Applied, 2nd ed. Boston: Little, Brown & Co. 1960.

    Google Scholar 

  • Reynolds, E.S.: The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. J. Cell Biol. 17, 208–212 (1963).

    Google Scholar 

  • Richardson, K.C.: Personal communication.

  • Schieffendecker, P.: Die Hautdrüsen des Menschen und der Säugetiere, ihre biologische und rassenanatomische Bedeutung sowie die Muscularis sexualis. Biol. Zbl. 37, 534–562 (1917).

    Google Scholar 

  • Shelley, W.B., and E.S. Levy: Histologic observations on the human apocrine sweat gland in health and disease. J. invest. Derm. 25, 249–264 (1955).

    Google Scholar 

  • Terzakis, J.A.: The ultrastructure of monkey eccrine sweat glands. Z. Zellforsch. 64, 493–509 (1964).

    Google Scholar 

  • Watson, M.L.: Staining of tissue sections for electron microscopy with heavy metals. J. biophys. biochem. Cytol. 4, 475–478 (1958).

    Google Scholar 

  • Weiner, J.S., and K. Hellman: The sweat glands. Biol. Rev. 35, 141–186 (1960).

    Google Scholar 

  • Yasuda, K., R.A. Ellis, and W. Montagna: The fine structural relationship between mitochondria and light granules in the human apocrine sweat gland. Okajimas Folia anat. jap. 38, 455–463 (1963).

    Google Scholar 

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Authors and Affiliations

  1. Department of Anatomy, Washington University School of Medicine, St. Louis, Missouri, USA

    Bryce L. Munger

  2. Department of Anatomy, University of Chicago, 60637, Chicago, Illinois, USA

    Bryce L. Munger

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  1. Bryce L. Munger
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Additional information

This investigation was supported in part by United States Public Health Service research grants GM-03784 and GM-10102 from the Institute of General Medical Sciences.

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Munger, B.L. The cytology of apocrine sweat glands. Zeitschrift für Zellforschung 67, 373–389 (1965). https://doi.org/10.1007/BF00339383

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  • DOI: https://doi.org/10.1007/BF00339383

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