Summary
The electron-microscopic observation of nerve cells of the rat hypothalamus, especially of nuclei paraventricularis and ventro-medialis, showed occasional nucleolus-like bodies in the cytoplasm, which are interpreted as a result of nucleolar extrusion, and not as artifact. The extruded nucleoli were different from the nuclear ones on possessing no nucleolonema structure, a fact that might be related to the disappearance of the pars amorpha and subsequent rearrangement of the constituent particles. The cytoplasmic nucleolus did not show any intimate relation to such organelles as mitochondria, endoplasmic reticulum and Golgi apparatus, but it seemed to release single ribosomes or polysomes from its periphery into the adjacent cytoplasm.
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Shimizu, N., Ishii, S. Electron-microscopic observations on nucleolar extrusion in nerve cells of the rat hypothalamus. Zeitschrift für Zellforschung 67, 367–372 (1965). https://doi.org/10.1007/BF00339382
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DOI: https://doi.org/10.1007/BF00339382