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The fine structure of the megakaryocyte of the bone marrow of the guinea pig

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Summary

The cytoplasm of megakaryocytes frequently exhibits bullate processes which protrude into the lumen of the sinusoids through small apertures in the reticular cells. These bullae differ morphologically from the platelet demarcation zones and are held to have a different function. It is concluded that the bullae detach from the megakaryocyte in a manner comparable to apocrine secretion and enter the blood stream.

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References

  • Bessis, M.: Cytology of the blood and blood-forming organs. New York: Grune & Stratton 1956.

    Google Scholar 

  • Finck, H.: Epoxy resins in electron microscopy. J. biophys. biochem. Cytol. 1, 27–30 (1960).

    Google Scholar 

  • Heidenhain, M.: Neue Untersuchungen über die Centralkörper und ihre Beziehungen zum Kern- und Zellenprotoplasma. Arch. mikr. Anat. 43, 473–758 (1894).

    Google Scholar 

  • Karnovsky, M. J.: Simple methods for “staining with lead” at high pH in electron microscopy. J. Cell Biol. 11, 729–732 (1961).

    Article  Google Scholar 

  • Luft, J. H.: Improvements in epoxy resins embedding methods. J. biophys. biochem. Cytol. 9, 409–414 (1961).

    Article  PubMed  Google Scholar 

  • Yamada, E.: The fine structure of the megakaryocyte in the mouse spleen. Acta anat. (Basel) 29, 267–290 (1957).

    Google Scholar 

  • Wright, J. H.: The histogenesis of the blood platelets. J. Morph. 21, 263–278 (1910).

    Google Scholar 

  • Zamboni, L., and D. C. Pease: The vascular bed of the red bone marrow. J. Ultrastruct. Res. 5, 65–85 (1961).

    PubMed  Google Scholar 

  • Zetterqvist, H.: The ultrastructural organization of the columnar absorbing cells of the mouse jejunum. Stockholm: Aktiebolaget Godvil 1956.

    Google Scholar 

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Authors and Affiliations

  1. Department of Anatomy, University of Chicago, Chicago, Illinois, USA

    Peter P. H. De Bruyn

Authors
  1. Peter P. H. De Bruyn
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Additional information

Dedicated to Professor Friedrich Wassermann with admiration and affection on the occasion of his 80th birthday.

This investigation was supported by a PHS research grant (CA 05493) from the U.S. Public Health Service.

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De Bruyn, P.P.H. The fine structure of the megakaryocyte of the bone marrow of the guinea pig. Z.Zellforsch 64, 111–118 (1964). https://doi.org/10.1007/BF00339190

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  • DOI: https://doi.org/10.1007/BF00339190

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