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Die Nervenendigungen der Rattenmuskelspindel im elektronen- und phasenkontrastmikroskopischen Bild

On the nerve, endings in the muscle spindle of the rat. An electronmicroscopical and phasemicroscopical investigation

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Zeitschrift für Zellforschung und Mikroskopische Anatomie Aims and scope Submit manuscript

Summary

By means of phase and electron microscopy five types of intrafusal nerve endings, showing differences in localisation and ultrastructure, are described. They can be divided into two groups.

  1. 1.

    Two kinds of endings show a neuromuscular contact approximately 150–350 Å wide and consisting of three layers but without a basement membrane between the membranes of the axon and the muscle fibre.

  2. 2.

    Three kinds of endings are characterised by a basement membrane and a synaptic cleft of about 1000 Å.

In comparison with the so far known results of the structural and functional behaviour of the various types of nerve endings in a muscle spindle it can be concluded that the first group of endings belongs to the sensory, and the second group to the motor innervation.

Zusammenfassung

Es wurden elektronen- und phasenkontrastmikroskopisch nach Lage und Feinstruktur fünf unterscheidbare Formen von Nervenendigungen an den intrafusalen Muskelfasern gefunden. Diese Endigungen lassen sich in zwei Gruppen einteilen:

  1. 1.

    Zwei Endigungsformen mit einem ca. 150–350 Å breiten, dreischichtigen, neuromuskulären Kontakt, ohne Basalmembran zwischen der Axonmembran und der Muskelfasermbran.

  2. 2.

    Drei Endigungsformen mit einem ca. 1000 Å breiten, fünfschichtigen, neuromuskulären Kontakt, mit Basalmembran im synaptischen Spalt zwischen Axonmembran und Muskelmembran.

Auf Grund des Vergleichs mit den bisher vorliegenden Ergebnissen über Bau und Funktion der verschiedenen Typen sensorischer und motorischer Endigungen ist anzunehmen, daß die erste Gruppe von Endigungen der sensorischen, die zweite der motorischen Innervation der intrafusalen Muskelfasern dient.

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Authors and Affiliations

  1. Senckenbergisches Anatomisches Institut der Universität, Frankfurt a. M.

    Gudrun Hennig

  2. Neurologisches Institut (Edinger-Institut) der Universität, Frankfurt a. M.

    Gudrun Hennig

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  1. Gudrun Hennig
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Die elektronenmikroskopischen Untersuchungen wurden im elektronenmikroskopischen Laboratorium der Neuropathologischen Abteilung des Max-Planck-Institutes für Hirnforschung durchgeführt. Herrn Dr.Schröder und den technischen Assistentinnen danke ich für die technische Beratung und Hilfe.

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Hennig, G. Die Nervenendigungen der Rattenmuskelspindel im elektronen- und phasenkontrastmikroskopischen Bild. Z. Zellforsch. 96, 275–294 (1969). https://doi.org/10.1007/BF00338773

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  • DOI: https://doi.org/10.1007/BF00338773

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