Summary
T(Y;2) translocations were used to cytologically localise the wingless locus of Drosophila melanogaster. We found that an existing T(Y;2), which is an insertion of a segment of 2L into the Y chromosome, has wg + within this insert. This Y chromosome was used to generate an attached XY chromosome containing wg +. The mutation claret-nondisjunctional (ca nd) was used to induce the loss of this XY chromosome and thus generate gynandromorphs with wg 1/wg 1 male tissue and wg +/wg 1/wg 1 female tissue. Analysis of these gynanders demonstrated that a genotypically wingless mutant hemithorax is usually also phenotypically mutant in these half body mosaics; thus wg 1 is discautonomous. This observation is of interest as it is known that wg is not cell autonomous.
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Communicated by C. Auerbach
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Babu, P., Bhat, S.G. Autonomy of the wingless mutation in Drosophila melanogaster . Mol Gen Genet 205, 483–486 (1986). https://doi.org/10.1007/BF00338086
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DOI: https://doi.org/10.1007/BF00338086