Summary
Lambda repressor was purified from an E. coli strain which produces 150 times more lambda repressor than a single lysogen. The sequence of the fifty N-terminal residues was determined by automated Edman degradation. It contains 43% of all arginine and lysine residues of the chain and constitutes according to the genetic data of Oppenheim et al. (1975) a substantial part of the operator-DNA-binding site of the repressor.
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References
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Communicated by H.G. Wittmann
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Beyreuther, K., Gronenborn, B. N-terminal sequence of phage lambda repressor. Molec. gen. Genet. 147, 115–117 (1976). https://doi.org/10.1007/BF00337945
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DOI: https://doi.org/10.1007/BF00337945