Chromosoma

, Volume 100, Issue 1, pp 37–47

The puff-specific Drosophila protein Bj6, encoded by the gene no-on transient A, shows homology to RNA-binding proteins

  • Hans von Besser
  • Petra Schnabel
  • Claudia Wieland
  • Elke Fritz
  • Ralf Stanewsky
  • Harald Saumweber
Chromosoma Focus
  • 45 Downloads

Abstract

The DNA coding for the puff-specific protein Bj6 has been isolated by expression cloning. The gene is localized in 14C1,2 on the X chromosome and is expressed ubiquitously during embryonic development with prominent expression during the first 12 h of embryogenesis. cDNA and genomic clones have been sequenced and show a single open-reading frame of 2.1 kb length, coding for a Mr=77000 basic protein. In the aminoterminal half of the protein we detect stretches of repeated amino acids, centrally a region with homology to RNA-binding proteins containing the RNP 1 and RNP 2 consensus motif of RNA binding proteins, and the carboxyterminal part is rich in charged amino acids. The Bj6 protein is a product of the gene no-on transient A, a gene required for normal vision and courtship behaviour in Drosophila.

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Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • Hans von Besser
    • 1
  • Petra Schnabel
    • 1
  • Claudia Wieland
    • 1
  • Elke Fritz
    • 1
  • Ralf Stanewsky
    • 1
  • Harald Saumweber
    • 1
  1. 1.Institut für Entwicklungsphysiologie Universität zu KölnKöln 41Federal Republic of Germany

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