Summary
Morphological and numerical variations of the pituitary gonadotrophs ß and γ were studied during 4 days cycles at different stages of the oestrous cycle in the Rat.
The highest degree of degranulation of the ß cells was observed first during the night of dioestrous II to prooestrous and afterwards on the afternon of prooestrous.
The degranulation of the γ cells began in the morning of prooestrous and reached its higher degree at 4 p. m. in prooestrous.
The first peak of degranulation of the ß cells was supposed to be related to the wave of follicular growth which occurs on the day of dioestrous II according to Long and Evans. The second phase of degranulation of these cells was considered as a prooestrous diurnal discharge of FSH synergically with the ovulatory discharge of LH by the γ cells during the critical period of the cycle.
Résumé
L'évolution des cellules gonadotropes préhypophysaires ß et γ a été étudiée au cours de cycles de 4 jours chez la ratte.
Ces 2 catégories cellulaires subissent au cours du cycle ovarien des variations morphologiques et numériques qui paraissent témoigner d'une activité folliculostimulante pour les cellules ß et d'une activité ovulatoire pour les cellules γ.
Les cellules ß se dégranulent une lère fois pendant la nuit du dioestrus II au prooestrus, puis une 2e fois, lors de la phase préovulatoire, l'après-midi du prooestrus.
Les cellules γ présentent, au cours de l'après-midi du prooestrus, une dégranulation massive, qui peut etre mise en rapport avec la décharge de L. H. qui se produit à ce stade du cycle.
La lère dégranulation des cellules ß en dioestrus II correspondrait à la vague de croissance folliculaire qui, selon Long et Evans, a lieu à ce stade du cycle et mènerait certains follicules à la rupture. La seconde traduirait une décharge de FSH synergique de l'excrétion de L. H. par les cellules γ, pendant la phase préovulatoire du cycle ovarien.
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Roos, J. Evolution des cellules gonadotropes préhypophysaires au cours du cycle oestral chez la ratte. Z. Zellforsch. 84, 372–388 (1967). https://doi.org/10.1007/BF00334753
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DOI: https://doi.org/10.1007/BF00334753