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On lipid droplets in renal interstitial cells

I. A histochemical study

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Summary

As the result of histochemical studies, it has been shown that the lipid droplets in the interstitial cells of the renal medulla of the rat contain simple saturated and unsaturated lipids. A possible correlation is suggested between the lipid droplets and the biologically active substances of a lipid character (vasodepressor lipid, medullin, and prostaglandin) which have been isolated from the renal medulla during recent years.

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References

  • Abrahams, C.: The ultrastructure of the interstitial tissue of the renal papilla of the rat. S. Afr. J. med. Sci. 29, 17–20 (1964).

    Google Scholar 

  • Allara, E., H. Elias, and P. M. Elias: The interstitial cells of the renal papilla. Anat. Rec. 151, 318 (1965).

    Google Scholar 

  • Andersen, H.: Development, morphology and histochemistry of the early synovial tissue in human foetuses. Acta anat. (Basel) 58, 90–115 (1964).

    Google Scholar 

  • Arnold, J.: Über Fettumsatz und Fettwanderung, Fettinfiltration und Fettdegeneration, Phagocytose, Metathese und Synthese. Virchows Arch. path. Anat. 171, 197–226 (1903).

    Google Scholar 

  • Barka, T., and P. J. Anderson: Histochemistry, theory, practice and bibliography. New York: Harper & Row Inc. 1965.

    Google Scholar 

  • Beer, A.: Die Bindesubstanz der menschlichen Niere im gesunden und krankhaften Zustande. Berlin: August Hirschwald 1859.

    Google Scholar 

  • Behnke, O., and J. Rostgaard: A device for mounting glass knives in the ordinary rotary microtome for sectioning plastic-embedded material. Stain Technol. 38, 299–300 (1963).

    Google Scholar 

  • Bennett, H. S., and J. H. Luft: S-collidine as a basis for buffering fixatives. J. biophys. biochem, Cytol. 6, 113–114 (1959).

    Google Scholar 

  • —, and R. M. Watts: The cytochemical demonstration and measurements of sulphydryl groups by azoaryl mercaptide coupling with special reference to mercury orange. In: General cytochemical methods, ed. by J. F. Danielli, vol. 1, p. 317–374. New York: Academic Press 1958.

    Google Scholar 

  • Björkman, N.: Low magnification electron microscopy in histological work. Acta. morph. neerl. scand. 4, 344–348 (1962).

    Google Scholar 

  • Blount, R. F., and I. H. Blount: The renal papilla of the immature mouse. Anat. Rec. 142, 217 (1962).

    Google Scholar 

  • Bowman, W.: The malpighian bodies of the kidney. Phil. Trans. P. 70–71 (1842).

  • Bulger, R. E., and B. Trump: Fine structure of the rat renal papilla. Amer. J. Anat. 118, 685–721 (1966).

    Google Scholar 

  • Chu, C. H. U.: A histochemical study of staining the axis cylinder with fuchsin-sulfurous acid (Schiffs reagent). Anat. Rec. 108, 723–745 (1950).

    Google Scholar 

  • Elftman, H.: Phospholipid fixation by dichromate-sublimate. Stain. Technol. 32, 29–31 (1957).

    Google Scholar 

  • Gloor, F., u. L. A. Neiditsch-Halff: Die Interstitiellen Zellen des Nierenmarks der Ratte. Z. Zellforsch. 66, 488–495 (1965).

    Google Scholar 

  • Hickler, R. B., D. P. Lauler, C. A. Saravis, A. I. Vagnucci, G. Steiner, and W. Thorn: Vasodepressor lipid from the renal medulla. Canad. med. Ass. J. 90, 280–287 (1964).

    Google Scholar 

  • Hori, S. H.: A simplified acid hematein test for phospholipids. Stain Technol. 38, 221–225 (1963).

    Google Scholar 

  • Kasten, F. H.: The chemistry of Schiff's reagent. Int. Rev. Cytol. 10, 1–100 (1960).

    Google Scholar 

  • —: Some comments on a recent criticism of the ninhydrin-Schiff reaction. J. Histochem. Cytochem. 10, 769–770 (1962).

    Google Scholar 

  • Kramer, H., and G. M. Windrum: The metachromatic staining reaction. J. Histochem. Cytochem. 3, 227–237 (1955).

    Google Scholar 

  • Lapp, H., u. A. Nolte: Vergleichende elektronmikroskopische Untersuchungen am Mark der Rattenniere bei Harnkonzentrierung und Harnverdünnung. Frankfurt. Path. 71, 617–633 (1962).

    Google Scholar 

  • Lee, J. B., B. G. Covino, B. H. Takman, and E. R. Smith: Chemical and physiological properties of medullin. Clin. Res. 13, 310 (1965).

    Google Scholar 

  • —: Renomedullary vasodepressor substance, medullin: Isolation, chemical characterization and physiological properties. Circulat. Res. 17, 57–77 (1965).

    Google Scholar 

  • Leeson, T. S.: An electron microscope study of the postnatal development of the hamster kidney. J. exp. Path. Invest. 10, 466–480 (1964).

    Google Scholar 

  • Liang, Hsu-Mu: A new method for staining nerves and their endings using the Schiff reaction. Anat. Rec. 99, 511–521 (1947).

    Google Scholar 

  • Lillie, R. D.: Histopathologic technic and practical histochemistry. New York: McGraw-Hill Book Co. 1954.

    Google Scholar 

  • Ludwig, C.: Von der Niere. In: Handbuch der Lehre von Gewebe des Menschen und der Tiere, ed. by S. Stricker, vol. 1, p. 505–507. Leipzig 1871.

  • Luft, J. H.: Improvements in epoxy resin embedding methods. J. biophysic. biochem. Cytol. 9, 409–414 (1961).

    Google Scholar 

  • Möllendorff, W. v.: Exkretionsorgane. In: Handbuch der Mikroskopischen Anatomie des Menschen, vol. VII/I. p. 140–143. Berlin: Springer 1930.

    Google Scholar 

  • Muehrcke, R. C., S. Rosen, and F. I. Volini: The interstitial cells of the renal papilla: Light and electronmicroscopic studies. In: Progress in pyelonephritis, ed. by E. H. Kass, p. 422–433. Philadelphia: F. A. Davis 1965.

    Google Scholar 

  • Novikoff, A. B.: The rat kidney: Cytochemical and electron microscopic studies. In: Biology of pyelonephritis, ed. by E. L. Quin and E. H. Kass, p. 113–144. Boston: Little Brown & Co. 1960.

    Google Scholar 

  • Osvaldo, L., and H. Latta: Insterstitial cells of the renal medulla. Anat. Rec. 151, 396 (1965).

    Google Scholar 

  • —: The interstitial cells of the renal medulla. J. Ultrastruct. Res. 15, 589–613 (1966).

    Google Scholar 

  • Pearse, A. G. E.: Histochemistry, theoretical and applied, 2. ed. London: J. & A. Churchill 1960.

    Google Scholar 

  • Policard, A.: Recherches histophysiologiques sur les premiers stades de la sécrétion urinaire. Arch. Anat. micr. Morph. exp. 14, 1–10 (1910).

    Google Scholar 

  • —: La cytogenese du tube urinaire chez l'homme. Arch. Anat. micr. Morph. exp. 14, 429–468 (1910).

    Google Scholar 

  • Schweigger-Seidel, F.: Die Nieren des Menschen und der Säugetiere in ihrem Feineren Bau. Halle: Buchhandl. des Waisenhauses 1865.

    Google Scholar 

  • Segawa, M.: Über die Fettarten der Niere mit besonderer Berücksichtigung des physiologischen Fettes. Beitr. path. Anat. 58, 1–47 (1914).

    Google Scholar 

  • Sternberg, W. H., E. Farber, and C. E. Dunlap: Histochemical localization of specific oxidative enzymes: II. Localization of diphosphopyridine nucleotide and triphosphopyridine nucleotide diaphorases and the succoindehydrogenase system in the kidney. J. Histochem. Cytochem. 4, 266–283 (1956).

    Google Scholar 

  • Vimtrup, B., and B. Schmidt-Nielsen: The histology of the kidney of kangaroo rats. Anat. Rec. 114, 515–528 (1952).

    Google Scholar 

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Authors and Affiliations

  1. Anatomy Department C, University of Copenhagen, Copenhagen Ø, Denmark

    R. Melchior Nissen

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  1. R. Melchior Nissen
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This work was supported by a grant from the Danish State Research Foundation.

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Nissen, R.M. On lipid droplets in renal interstitial cells. Z. Zellforsch. 83, 76–81 (1967). https://doi.org/10.1007/BF00334742

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  • DOI: https://doi.org/10.1007/BF00334742

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