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Effects of low and moderate intensity treadmill walking on postprandial lipaemia in healthy young adults

  • N. V. Tsetsonis
  • A. E. Hardman
Original Article

Abstract

We have previously shown that the lipaemic response to a fatty meal was reduced when prolonged (2 h) low intensity exercise was taken some hours before eating. The purpose of this study was to test the hypothesis that the effect is quantitatively greater after exercise of moderate intensity than after exercise at low intensity. Six men and six women, mean age 26.9 (SEM 1.5) years, took part in three trials, each conducted over 2 days; on the afternoon of day 1 of each of two exercise trials the subjects walked on a treadmill for 90 min at either 31 (SEM 1) % or 61 (SEM 1) % of maximal oxygen uptake, i.e. low and moderate intensity, respectively; on the control trial the subjects refrained from exercise on day 1. On the morning of day 2 of each trial they ingested a test meal (1.28 g fat, 1.44 g carbohydrate, 76 kJ energy · kg−1 body mass); blood samples were obtained in the fasted state and for 6 h after the meal. Fasting serum triacylglycerol concentration and the area under the postprandial triacylglycerol-time curve were lower than in the control trial (P < 0.05) after moderate intensity walking but not after low intensity walking. The results suggest that the mitigation of the lipaemic response to a meal high in fat and carbohydrate is related to the intensity and/or the energy expenditure of the preceding exercise.

Key words

Postprandial Triacylglycerol Walking Exercise intensity 

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References

  1. Aldred HE, Hardman AE (1993) Reproducibility of oral fat tolerance tests. Nutr Clin Metab 7:261Google Scholar
  2. Aldred HE, Perry IC, Hardman AE (1994) The effect of a single bout of brisk walking on postprandial lipaemia in normolipidaemic young adults. Metabolism 43:836–841Google Scholar
  3. Annuzzi G, Janssen E, Kaijser L, Holmquist L, Carlson LA (1987) Increased removal rate of exogenous triglycerides after prolonged exercise in man: time course and effect of exercise duration. Metabolism 36:438–443Google Scholar
  4. Blair SN, Kohl HW, Gordon NF (1992) How much physical activity is good for health? Ann Rev Public Health 13:99–126Google Scholar
  5. Borg GA (1973) Perceived exertion: a note on history and methods. Med Sci Sports 5:90–93Google Scholar
  6. Brunzell JD, Hazzard WR, Porte D, Bierman EL (1973) Evidence for a common, saturable, triglyceride removal mechanism for chylomicrons and very low density lipoproteins in man. J Clin Invest 52:1578–1585Google Scholar
  7. Burnett RA, Aldred HE, Hardman AE (1993) Influence of the intensity of prior exercise on postprandial lipaemia in man. Proc Nutr Soc 52:284AGoogle Scholar
  8. Chinnici JC, Zauner CW (1971) The effect of two intensities of exercise on the magnitude and duration of postprandial lipemia. J Sports Med 11:36–41Google Scholar
  9. Dill DB, Costill DL (1974) Calculation of percentage changes in volumes of blood, plasma and red cells in dehydration. J Appl Physiol 37:247–248Google Scholar
  10. Farese RV, Yost TJ, Eckel RH (1991) Tissue-specific regulation of lipoprotein lipase activity by insulin/glucose in normal-weight humans. Metabolism 40:214–216Google Scholar
  11. Gidez LI, Miller GJ, Burstein M, Slage S, Eder HA (1982) Separation and quantification of subclasses of human plasma high density lipoproteins by a simple precipitation procedure. J Lipid Res 23:1206–1223Google Scholar
  12. Gordon PM, Goss FL, Visich PS, Warty V, Denys BJ, Metz KF, Robertson RJ (1994) The acute effects of exercise intensity on HDL-C metabolism. Med Sci Sports Exerc 26:671–677Google Scholar
  13. Groot PHE, Stiphout WAHJ van, Krauss HJ, Tol A van, Ramshorst E van, Chin-On S, Hofman A, Cresswell SR, Havekes L (1991) Postprandial lipoprotein metabolism in normolipidemic men with and without coronary artery disease. Arterioscl Thromb 11:653–662Google Scholar
  14. Hardman AE, Aldred HE (1995) Walking during the post-prandial period decreases alimentary lipaemia. J Cardiovasc Risk 2:71–78Google Scholar
  15. Haskell WL (1994) Health consequences of physical activity: understanding and challenges regarding dose-response. Med Sci Sports Exerc 26:649–660Google Scholar
  16. Honig CR (1979) Contributions of nerves and metabolites to exercise vasodilation: a unifying hypothesis. Am J Physiol 236: H705-H719Google Scholar
  17. Kantor MA, Cullinane EM, Sady SP, Herbert PN, Thompson PD (1987) Exercise acutely increases high density lipoprotein cholesterol and lipoprotein lipase activity in trained and untrained men. Metabolism 36:188–192Google Scholar
  18. Karpe F, Steiner G, Uffelman K, Olivecrona T, Hamsten A (1994) Postprandial lipoproteins and progression of coronary atherosclerosis. Atherosclerosis 106:83–97Google Scholar
  19. Katzel LI, Busby-Whitehead MJ, Rogus EM, Krauss RM, Goldberg AP (1994) Reduced adipose tissue lipoprotein lipase responses, postprandial lipemia, and low high density lipoprotein-2 subspecies levels in older athletes with silent myocardial ischemia. Metabolism 43:190–198Google Scholar
  20. Kiens B, Lithell H, Mikines KJ, Richter EA (1989) Effects of insulin and exercise on muscle lipoprotein lipase activity in man and its relation to insulin action. J Clin Invest 84:1124–1129Google Scholar
  21. Lithell H, Cedermark M, Fröberg J, Tesch P, Karlsson J (1981) Increase of lipoprotein lipase activity in skeletal muscle during heavy exercise. Relation to epinephrine excretion. Metabolism 30:1130–1134Google Scholar
  22. Maughan RJ (1982) A simple, rapid method for the detection of glucose, lactate, pyruvate, alanine, 3-hydroxybutyrate and acetoacetate on a single 20 µl blood sample. Clin Chim Acta 122:231–240Google Scholar
  23. Nikkila EA, Konttinen A (1962) Effect of physical activity on postprandial levels of fats in serum. Lancet I:1151–1152Google Scholar
  24. Oscai LB, Essig DA, Palmer WK (1990) Lipase regulation of muscle triglyceride hydrolysis. J Appl Physiol 69:1571–1577Google Scholar
  25. Patsch JR (1994) Triglyceride-rich lipoproteins and atherosclerosis. Atherosclerosis 110 [Suppl]:S23-S26Google Scholar
  26. Patsch JR, Karlin JB, Scott LW, Smith LC, Gotto AM (1983) Inverse relationship between blood levels of high density lipoprotein subfraction 2 and magnitude of postprandial lipemia. Proc Natl Acad Sci USA 80:1449–1453Google Scholar
  27. Patsch JR, Prasad S, Gotto AM, Patsch W (1987) High density lipoprotein 2: relationship of the plasma levels of this lipoprotein to its composition, to the magnitude of postprandial lipemia and to the activities of lipoprotein lipase and hepatic lipase. J Clin Invest 80:341–347Google Scholar
  28. Patsch JR, Miesenböck G, Hopferwiser T, Muhlberger V, Knapp E, Dunn JK, Gotto AM, Patsch W (1992) Relation of triglyceride metabolism and coronary artery disease. Studies in the postprandial state. Arterioscl Thromb 12:1336–1345Google Scholar
  29. Potts JL, Fisher RM, Humphreys SM, Coppack SW, Gibbons GF, Frayn KN (1991) Peripheral triacylglycerol extraction in the fasting and post-prandial states. Clin Sci 81:621–626Google Scholar
  30. Romijn JA, Coyle EF, Sidossis LS, Gastaldelli A, Horowitz JF, Endert E, Wolfe RR (1993) Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration. Am J Physiol 265:E380-E391Google Scholar
  31. Rossner S (1974) Studies on an intravenous fat tolerance test: methodological, experimental and clinical experiences with Intralipid. Acta Med Scand 564 [Suppl]:3–24Google Scholar
  32. Sady SP, Thompson PD, Cullinane EM, Kantor MA, Domagala E, Herbert PN (1986) Prolonged exercise augments plasma triglyceride clearance. J Am Med Assoc 256:2552–2555Google Scholar
  33. Schlierf G, Dinsenbacher A, Kather H, Haberbosch W (1987) Mitigation of alimentary lipemia by postprandial exercise. Phenomena and mechanisms. Metabolism 36:726–730Google Scholar
  34. Simpson HS, Williamson CM, Olivecrona T, Pringle S, Maclean J, Lorimer AR, Bonnefous F, Bogaievsky Y, Packard CJ, Shepherd J (1990) Postprandial lipemia, fenofibrate and coronary artery disease. Atherosclerosis 85:193–200Google Scholar
  35. Taylor HL, Buskirk E, Henschel A (1955) Maximal oxygen intake as an objective measure of cardio-respiratory performance. J Appl Physiol 8:73–80Google Scholar
  36. Weintraub MS, Eisenberg S, Breslow JL (1987) Different patterns of postprandial lipoprotein metabolism in normal, type IIa, type III, and type IV hyperlipoproteinemic individuals. Effects of treatment with Cholestyramine and Gemfibrozil. J Clin Invest 79:1110–1119Google Scholar
  37. Zilversmit DB (1979) Atherogenesis: a postprandial phenomenon. Circulation 60:473–485Google Scholar

Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • N. V. Tsetsonis
    • 1
  • A. E. Hardman
    • 1
  1. 1.Department of Physical Education, Sports Science and Recreation ManagementLoughborough UniversityLoughborough, LeicestershireEngland

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