Summary
The nucleotide sequence of the gene encoding group A streptococcal pyrogenic exotoxin type A (SPE A) was determined by the dideoxy chain termination method. The first 30 residues of the translation product represented a hydrophobic signal peptide. The mature protein was 220 amino acids in length and had a molecular weight of 25,805. It has significant protein sequence homology with Staphylococcus aureus enterotoxin B but not with other proteins in the Dayhoff library.
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References
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Communicated by J.W. Lengeler
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Johnson, L.P., L'Italien, J.J. & Schlievert, P.M. Streptococcal pyrogenic exotoxin type A (scarlet fever toxin) is related to Staphylococcus aureus enterotoxin B. Molec Gen Genet 203, 354–356 (1986). https://doi.org/10.1007/BF00333979
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DOI: https://doi.org/10.1007/BF00333979