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Genetic control of the arginine pathways in Aspergillus nidulans

Common regulation of anabolism and catabolism

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Summary

Two regulatory mutants for arginine catabolism isolated as proline suppressors were tested for the synthesis of ornithine transcarbamylase (OTC), the arginine anabolic enzyme. Mutations at one locus, suD, result in the insensitivity of OTC synthesis to effectors responsible for the enzyme level in the wild strain. The common genetic regulation of both catabolic and anabolic pathways of arginine is postulated.

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Authors and Affiliations

  1. Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland

    J. Cybis, M. Piotrowska & P. Weglenski

  2. Department of Genetics, University of Warsaw, Warsaw, Poland

    J. Cybis, M. Piotrowska & P. Weglenski

Authors
  1. J. Cybis
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  2. M. Piotrowska
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  3. P. Weglenski
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Communicated by F. Kaudewitz

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Cybis, J., Piotrowska, M. & Weglenski, P. Genetic control of the arginine pathways in Aspergillus nidulans . Molec. gen. Genet. 118, 273–277 (1972). https://doi.org/10.1007/BF00333463

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  • DOI: https://doi.org/10.1007/BF00333463

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