Summary
Lumbar myelography with iohexol (Omnipaque) was performed in 103 consecutive adult patients with low back pain or sciatica. The patients were observed for 48 h with registration of possible adverse reactions. Mild or moderate transient side effects were recorded in 24 patients. No serious adverse reactions were noted, and EEG recorded in 25 patients showed no changes.
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References
Gonsette RE (1981) The neurotoxicity of Water-soluble contrast media; actual concepts and future. Amiel Contrast media in radiology. First European Workshop Lyon. pp 115–122
Siefert HM, Press WR, Speck U (1980) Tolerance to iohexol after intracisternal, intracerebral and intraarterial injection in the rat. Acta Radiol [Suppl] (Stockh) 362:77–82
Golman K, Olivecrona H, Gustafson C, Salvesen S, Almen T, Maly P (1980) Excitation and depression of nonanaesthetized rabbits following injection of contrast media into the subarachnoid space. Acta Radiol [Suppl] (Stockh) 362:83–86
Salvesen S (1981) Intracisternal toxicity in rats. A comparison of the effects of iohexol, iopamidol, ioxaglate and physiological saline. Nyegaard, Oslo
Duprey LP, Piller RN, Fabian RJ, Drobeck HP (1981) Acute intracisternal toxicity of Win 39, 424 (iohexol) in male mice. Sterling-Winthrop Research Institute, New York
Duprey LP (1981) Effect of repeated intracisternal injection of Win 39, 424 (iohexol) in Cynomolgus monkeys — five weekly injections. Sterling-Winthrop Research Institute, New York
Gonsette RE (1981) Immediate and delayed neurotoxicity of newly synthesized contrast media demonstrated by EEG sequential analysis. Amiel Contrast media in radiology. First European Workshop Lyon. pp 141–148
Eldevik OP, Nakstad P, Kendall BE, Hindmarsh T (1983) Iohexol in lumbar myelography: Preliminary results from an open non-comparative multicenter clinical study. AJNR 4: 299–301
Lossius R, Eldevik OP, Weber H, Oftedal SI, Strømme JH (1983) First clinical trial with iohexol in myelography. Acta Radiol [Diagn] 24 (6):499–502
Skalpe IO, Torbergsen T, Amundsen P, Presthus J (1973) Lumbar myelography with metrizamide. Acta Radiol [Suppl] (Stockh) 335:367–379
Gonsette RE (1973) Metrizamide as contrast medium for myelography and ventriculography. Acta Radiol [Suppl] (Stockh) 335:346–358
Kendall B, Schneidan A, Stevens J, Harrison M (1983) Clinical trial of iohexol for lumbar myelography. Br J Radiol 56: 539–542
Dugstad G, Eldevik P (1973) Lumbar myelography. Acta Radiol [Suppl] (Stockh) 335:11–30
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Lilleås, F., Bach-Gansmo, T. & Weber, H. Lumbar myelography with omnipaque (iohexol). Neuroradiology 28, 344–346 (1986). https://doi.org/10.1007/BF00333442
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DOI: https://doi.org/10.1007/BF00333442