Skip to main content
SpringerLink
Log in

Ant-mediated transactivation of early genes in Salmonella prophage P22 by superinfecting virulent P22 mutants

  • Short Communication
  • Published:
Molecular and General Genetics MGG Aims and scope Submit manuscript

Summary

The virulent mutants P22 vir B vy and P22 vy mutants, both insensitive to mnt-repressor, transactivate the early genes of a P22 prophage. The transactivation of early P22 prophage genes depends strictly on the expression of gene ant (“antirepressor”-protein) by the superinfecting P22 mutant and therefore occurs by derepression.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Botstein, D., Lew, K.K., Jarvik, V., Swanson, C.A., Jr.: Role of antirepressor in the bipartite control of repression and immunity by bacteriophage P22. J. molec. Biol. 91, 439–462 (1975)

    Google Scholar 

  • Bronson, M.J., Levine, M.: Virulent mutants of bacteriophage P22 I. Isolation and genetic analysis. J. Virol. 7, 559–568 (1971)

    Google Scholar 

  • Bronson, M.J., Levine, M.: Virulent Mutants of Phage P22. II. Physiological Analysis of P22 vir B-3 and Its Component Mutations. Virology 47, 644–655 (1972)

    Google Scholar 

  • Hilliker, S., Botstein, D.: An early regulatory gene of Salmonella phage P22 analogous to gene N of Coliphage λ. Virology 68, 510–524 (1975)

    Google Scholar 

  • Hilliker, S., Botstein, D.: Specificity of genetic elements controlling regulation of early functions in temperate bacteriophages. J. molec. Biol. 106, 537–566 (1976)

    Google Scholar 

  • Levine, M., Truesdell, S., Ramakrishnan, T., Bronson, M.J.: Dual control of lysogeny by bacteriphage P22: An antirepressor locus and its controlling elements. J. molec. Biol. 91, 421–438 (1975)

    Google Scholar 

  • Prell, H.H.: Px, a hybrid between the serological unrelated and heteroimmune Salmonella bacteriophages P22 and Py. II. Contribution of P22 genetic material to different Px variants. Molec. gen. Genet. 108, 184–202 (1970)

    Google Scholar 

  • Prell, H.H.: Px, a hybrid between the serological unrelated and heteroimmune Salmonella bacteriophages P22 and Py. I. Some properties of Py and Px, genetic evidence for the hybrid nature of Px1 and phenotypic, mixing between P22, Py and Px. Molec. gen. Genet. 108, 167–183 (1970a)

    Google Scholar 

  • Prell, H.H.: Regulation of gene expression in Salmonella phage P22.I. Genetic experiments involving P22 and Py. Molec. gen. Genet. 127, 327–339 (1973)

    Google Scholar 

  • Prell, H.H.: Regulation of gene expression in Salmonella phage P22. II. Regulation of expression of late functions. Molec. gen. Genet. 136, 351–360 (1975)

    Google Scholar 

  • Prell, H.H.: The role of ant-product of Salmonella phage P22 in the process of transactivation of prophage Pxl genes. Molec. gen. Genet. 156, 61–69 (1977)

    Google Scholar 

  • Rao, R.N.: Bacteriophage P22 controlled exclusion in Salmonella typhimurium. J. molec. Biol. 35, 607–622 (1968)

    Google Scholar 

  • Susskind, M.M., Botstein, D., Wright, A.: Superinfection exclusion by P22 prophage in lysogens of Salmonella typhimurium. III. Failure of superinfecting phage DNA to enter sieA+ lysogens. Virology 62, 350–366 (1974)

    Google Scholar 

  • Susskind, M.M., Wright, A., Botstein, D.: Superinfection exclusion by P22 prophage in lysogens of Salmonella typhimurium. II. Genetic evidence for two exclusion systems. Virology 45, 638–652 (1971)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Abt. für Molekulare Genetik im Institut für Mikrobiologie der Gesellschaft für Strahlen- und Umweltforschung mbH München in Göttingen, Grisebachstr. 8, D-3400, Göttingen, Federal Republic of Germany

    Hermann H. Prell

Authors
  1. Hermann H. Prell
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Communicated by F. Stahl

Rights and permissions

Reprints and permissions

About this article

Cite this article

Prell, H.H. Ant-mediated transactivation of early genes in Salmonella prophage P22 by superinfecting virulent P22 mutants. Molec. Gen. Genet. 164, 331–334 (1978). https://doi.org/10.1007/BF00333164

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00333164

Keywords

Search

Navigation