Summary
SP50 DNA (M. W.=97×106 Daltons) shows an unusual shear lability. At low shear rates SP50 DNA is more susceptible to hydrodynamic shear than the longer T2 DNA (M. W.=130×106 Daltons). This unusual fragility of SP50 DNA is atributed to the presence of a small number of weak points in SP50 DNA. Most likely these weak points are identical with the single-strand breaks in SP50 DNA.
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Communicated by P. Starlinger
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Creeger, E.S., Spatz, H.C. The anomalous shear lability of SP 50 DNA. Molec. Gen. Genetics 106, 25–31 (1969). https://doi.org/10.1007/BF00332818
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DOI: https://doi.org/10.1007/BF00332818