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A survey of a familial transmission of an anomalous autosome in group 13–15

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Abstract

A male child hospitalized due to undescended testes (cryptorchism) was found to possess an abnormal autosome with an unusually elongated short arm in group 13–15. A familial chromosome investigation undertaken in 14 persons related to the propositus in his paternal line and in his mother revealed that his clinically normal father, grandfather, 2 aunts and a female cousin carried the same aberrant autosome. It is evident that a carrier of the abnormal chromosome is the grandfather, that the anomalous element was transmitted, irrespective of sex, from the parents either one of whom carried the aberrant one, and that the particular autosomal abnormality is not always associated with specific phenotypic anomaly. A possible origin of the aberrant autosome is discussed.

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Contribution no. 733 from the Zoological Institute, Faculty of Science, Hokkaido University, Sapporo.

The senior author (S. M.) wishes to dedicate this paper to Dr. Jakob Seiler on the occasion of his 80th birthday, May 16, 1966.

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Makino, S., Muramoto, J.i. & Tabata, S. A survey of a familial transmission of an anomalous autosome in group 13–15. Chromosoma 18, 371–379 (1966). https://doi.org/10.1007/BF00332543

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  • DOI: https://doi.org/10.1007/BF00332543

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