Abstract
The synthesis of DNA does not proceed in a perfectly synchronous way in about 20% of the binucleate cells induced in Allium sativum L. root meristems by treatment with methyl 3 hydroxy 6 (1 H, 3 H) quinazoline dione, 2.4 (an inhibitor of cytokinesis). — Nuclear labelling after tritiated thymidine incorporation and the measurement of nuclear DNA by cytophotometry both establish that the beginning of the S phase as well as its duration may be different in the two nuclei included in a single cytoplasm. Yet the nuclear synchronism progressively asserts itself as the cell cycle goes on and, following this asynchronous synthesis, the beginning of mitosis is synchronous. The restoration of such a coordination points to the existence in the cytoplasm of separable factors inducing DNA synthesis and mitosis.
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Benbadis, M.C., Ribsztejn, M. & Deysson, G. The mode of nuclear DNA synthesis in experimentally induced binucleate cells of root meristems. Chromosoma 46, 1–11 (1974). https://doi.org/10.1007/BF00332334
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DOI: https://doi.org/10.1007/BF00332334