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Eimeria tenella: Chemotherapeutic studies in chick embryos with a description of a new method (chorioallantoic membrane foci counts) for evaluating infections

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Summary

The examination of two laboratory strains of E. tenella show that they differ in their response to several drugs when examined by the chick embryo infection technique. Another strain of E. tenella, recently isolated from the field, was markedly resistant to four quinoline compounds but was controlled by the pyrinidone compound “Clopidol” and a new anticoccidial “Robenzidene”. It is suggested that chick embryo infections provide a means of comparing the degree of drug tolerance by different strains of E. tenella on a quantitative basis.

A new method is described for the evaluation of antiparasitic substances by counting the macroscopic focal lesions on the chorioallantois associated with schizogony of E. tenella. This procedure appears to be more sensitive than the use of mortality for the evaluation of effects on E. tenella.

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References

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Authors and Affiliations

  1. Houghton Poultry Research Station, Houghton, Huntingdon, England

    P. L. Long

  2. Brunel University, London

    P. L. Long

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  1. P. L. Long
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Long, P.L. Eimeria tenella: Chemotherapeutic studies in chick embryos with a description of a new method (chorioallantoic membrane foci counts) for evaluating infections. Z. Parasitenk. 33, 329–338 (1970). https://doi.org/10.1007/BF00331469

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  • DOI: https://doi.org/10.1007/BF00331469

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