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Pi M4: An additional Pi M subtype

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The authors studied Pi polymorphism using the Separator isofocusing method with slight modification. A new Pi allele was observed. Family pedigrees confirmed co-dominant inheritance with other Pi alleles. According to the electrophoretic mobility of its isoprotein bands, and to its frequency (0.04) this new allele is considered as a fourth Pi M subtype: Pi M4.

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Constans, J., Viau, M. & Gouaillard, C. Pi M4: An additional Pi M subtype. Hum. Genet. 55, 119–121 (1980). https://doi.org/10.1007/BF00329137

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