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MRI study of Baló's concentric sclerosis before and after immunosuppressive therapy

Summary

An intra vitam diagnosis of Baló's concentric sclerosis in a 39-year-old male is described. To our knowledge this is the first reported case of ante-mortem diagnosis based solely on magnetic resonance imaging (MRI) findings. MRI showed features unique to this process. After high-dose intravenous therapy with prednisone, the clinical symptoms improved, and MRI showed marked changes of the concentric lesions.

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Spiegel, M., Krüger, H., Hofmann, E. et al. MRI study of Baló's concentric sclerosis before and after immunosuppressive therapy. J Neurol 236, 487–488 (1989). https://doi.org/10.1007/BF00328514

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  • DOI: https://doi.org/10.1007/BF00328514

Key words

  • Baló's concentric sclerosis
  • Magnetic resonance imaging
  • Oligoclonal CSF IgG banding