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Recombination between repeated DNA sequences occurs more often in plasmids than in the chromosome of Bacillus subtilis

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Summary

Directly repeated pBR322 sequences 3.7–3.8 kb long recombine with a frequency of about 10% per generation when carried on plasmids related to pC194 and 0.01% per generation when carried on the Bacillus subtilis chromosome. Recombination is therefore 1,000 times more efficient in plasmids than in the chromosome of this organism.

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Author notes

  1. B. Niaudet

    Present address: Institut Pasteur, 28, rue du Docteur Roux, F-75724, Paris Cedex 15, France

Authors and Affiliations

  1. Institut Jacques Monod, C.N.R.S., Université Paris VII, 2, Place Jussieu, 75251, Paris Cedex 05, France

    B. Niaudet, L. Jannière & S. D. Ehrlich

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  1. B. Niaudet
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  2. L. Jannière
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  3. S. D. Ehrlich
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Communicated by H. Saedler

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Niaudet, B., Jannière, L. & Ehrlich, S.D. Recombination between repeated DNA sequences occurs more often in plasmids than in the chromosome of Bacillus subtilis . Mol Gen Genet 197, 46–54 (1984). https://doi.org/10.1007/BF00327921

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  • DOI: https://doi.org/10.1007/BF00327921

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