Summary
The safety of post-myelogram computed tomography (PMCT) as an additional diagnostic procedure to metrizamide myelography was evaluated. One hundred and four consecutive patients with suspected cervical cord lesions were studied prospectively; 50 had both myelography and PMCT, and the 54 acting as controls had only myelography. PMCT did not increase the incidence, severity or duration of common side effects and the majority of patients accepted this additional procedure. It is concluded that as long as care is taken to avoid the occurrence of excessive contrast in the intracranial subarachnoid space, PMCT is a safe procedure.
Similar content being viewed by others
References
Di Chiro G, Schellinger D (1976) Computed tomography of spinal cord after lumbar intrathecal introduction of metrizamide (computer-assisted myelography). Radiology 120: 101–104
Forbes WStC, Isherwood I (1978) Computed tomography in syringomyelia and the associated Arnold-Chiari type 1 malformation. Neuroradiology 15: 73–78
Rësjo MI, Harwood-Nash DC, Fitz CR, Chuang S (1979) Computed tomographic metrizamide myelography in syringomyelia. Radiology 131: 405–407
Bonafé A, Manelfe C, Espagno J, Guiraud B, Rascol A (1980) Evaluation of syringomyelia with metrizamide computed tomographic myelography. J Comput Assist Tomogr 4: 797–802
Seibert CE, Dreisbach JN, Swanson WB, Edgar RE, Williams P, Hahn H (1981) Progressive posttraumatic, cystic myelopathy: neuroradiologic evaluation. AJNR 2: 115–119
Coin CG, Chan Y-S, Keranen V, Pennink M (1977) Computer assisted myelography in disk disease. J Comput Assist Timogr 1: 398–404
Yu YL, Stevens JM, Kendall B, du Boulay GH (1983) Cord shape and measurements in cervical spondylotic myelopathy and radiculopathy. AJNR 4(3): 839–842
Miyasaka K, Isu T, Iwasaki, Y, Abe S, Takei H, Tsurn M (1983) High resolution computed tomography in the diagnosis of cervical dise disease. Neuroradiology 24: 253–258
Aubin ML, Jardin C, Bar D, Vignand, J (1979) Computed tomography in 32 cases of intraspinal tumour. J de Neuroradiol 6: 81–92
Roub LW, Drayer BP (1979) Spinal computed tomography: limitations and applications. AJNR 133: 267–273
Hindmarsh T, Grene A, Widen L (1975) Metrizamide-phenothiazine interaction. Acta Radiol Diag 16: 129–134
Amundsen P (1977) Metrizamide in cervical myelography. Acta Radiol [Suppl] 355: 85–97
Skalpe IO (1977) Adverse effects of water soluble contrast media in myelography, cisternography and ventriculography: a review with special reference to metrizamide. Acta Radiol [Suppl] 355: 359–370
Sackett JF, Strother CM, Quaglieri CE, Javid MJ, Levin AB, Duff TA (1977) Metrizamide—CSF contrast medium. Radiology 123: 779–782
Bastow M, Godwin-Austin RB (1979) Cervical myelopathy after metrizamide myelography. Br Med J 2: 1262–1263
Paling MR, Quindlen EA, Di Chiro G (1980) Spinal seizures after metrizamide myelography in a patient with a spinal block. AJNR 1: 473–474
Vincent FM, Zimmerman JE (1980) Metrizamide encephalopathy. Ann Neurol 7: 494
Bergstrom K, Mostrom U (1977) Technique for cervical myelography with metrizamide. Acta Radiol [Suppl] 355: 105–109
Nielsen H (1975) Epileptic seizures following cervical myelography. Neuroradiology 10: 59–60
Sortland O, Lundervold A, Nesbakken R (1977) Mental confusion and epileptic seizures following cervical myelography with metrizamide. Report of a case. Acta Radiol [Suppl] 355: 403–406
Tourtelotte WW, Haerrer AF, Heller GL, Somers JE (1964) Post lumbar puncture headaches. Charles Thomas Publisher, Springfield, Illinois
Potts DG, Gomez DG, Abbott GF (1977) Possible causes of complications of myelography with water-soluble contrast medium. Acta Radiol [Suppl] 355: 390–402
Skalpe IO (1980) Metrizamide myelography. In: Post MJD ed. Radiographic evaluation of the spine. Masson Publishing, New York pp 514–532
Eldevik OP, Nakken KO, Haughton VM (1978) The effect of dehydration on the side effects of metrizamide myelography. Radiology 129: 715–716
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Yu, Y.L., du Boulay, G.H. Is there an increased risk of early side effects of metrizamide in post-myelogram computed tomography?. Neuroradiology 26, 399–403 (1984). https://doi.org/10.1007/BF00327494
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00327494