Abstract
Many long-established laboratory strains of D. melanogaster interact with recently-collected wild-type strains, so that the progeny show sterility, enhanced mutation, male recombination and other degenerative traits, a syndrome known collectively as “hybrid dysgenesis”. Tests have been made for differences in centromeric heterochromatin between interacting strains, by comparing homologues in mitotic preparations from hybrid individuals. Differences between homologues have not been revealed, either qualitatively by C-banding or quantitatively by in situ hybridisation to RNA transcripts from satellites 1.705 and 1.686. However, the sensitivities of the techniques are such that quantitative differences of less than 50% between strains could escape detection.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Bedo, D.G.: C Banding in polytene chromosomes of Simulium ornatipes and S. melatum (Diptera: Simuliidae). Chromosoma (Berl.) 51, 291–300 (1975)
Brutlag, D., Carlson, M., Fry, K., Hsieh, T.S.: DNA sequence organisation in Drosophila heterochromatin. Cold Spr. Harb. Symp. quant. Biol. 42, 1137–1146 (1978)
Bucheton, A.: Non-Mendelian female sterility in Drosophila melanogaster: influence of ageing and thermic treatments. I. Evidence for a partly heritable effect of these two factors. Heredity 41, 357–369 (1978)
Burns, J.A., Gerstel, D.U.: Flower color variegation and instability of a block of heterochromatin in Nicotiana. Genetics 57, 155–167 (1967)
Colgan, D.J., Angus, D.S.: Bisexual hybrid sterility in Drosophila melanogaster. Genetics 89, 5–14 (1978)
Faccio Dolfini, S.: Karyotype evolution in cell lines of Drosophila melanogaster. Chromosoma (Berl.) 58, 73–86 (1976)
Green, M.M.: Genetic instability in Drosophila melanogaster: De novo induction of putative insertion mutants. Proc. nat. Acad. Sci. (Wash.) 74, 3490–3493 (1977)
John, B., King, M.: Heterochromatin variation in Cryptobothrus chrysophorus. II. Patterns of C-banding. Chromosoma (Berl.) 65, 59–79 (1977)
Kidwell, M.G., Kidwell, J.F., Sved, J.A.: Hybrid dysgenesis in Drosophila melanogaster: a syndrome of aberrant traits including mutation, sterility and male recombination. Genetics 86, 813–833 (1977)
Kurnit, D.M.: Satellite DNA and heterochromatin variants: the case for unequal mitotic crossing over. Hum. Genet. 47, 169–186 (1979)
Marshall Graves J.A.,: DNA synthesis in chromosomes of cultured leucocytes from two marsupial species. Exp. Cell Res. 46, 37–57 (1967)
Matthews, K.A., Hiraizumi, Y.: An analysis of male-recombination elements in a natural population of Drosophila melanogaster in South Texas. Genetics 88, 81–91 (1978)
Pardue, M.L., Gall, J.G.: Chromosomal location of mouse satellite DNA. Science 168, 1356–1358 (1970)
Peacock, W.J., Brutlag, D.L., Goldring, E., Appels, R., Hinton, C.W., Lindsley, D.L.: The organisation of highly repeated DNA sequences in Drosophila melanogaster chromosomes. Cold Spr. Harb. Symp. quant. Biol. 38, 405–416 (1974)
Peacock, W.J., Lohe, A.R., Gerlach, W.L., Dunsmuir, P., Dennis, E.S., Appels, R.: Fine structure and evolution of DNA in heterochromatin. Cold Spr. Harb. Symp. quant. Biol. 42, 1121–1135 (1978)
Picard, G.: Non-mendelian female sterility in Drosophila melanogaster: Hereditary transmission of I factor. Genetics 83, 107–123 (1976)
Picard, G.: Non-mendelian female sterility in Drosophila melanogaster: principal characteristics of chromosomes from inducer and reactive origin after chromosomal contamination. Genetics 91, 473–489 (1979)
Rhoades, M.M.: Genetic effects of heterochromatin in maize. In: Maize breeding and genetics (D.B. Walden, ed.), pp. 641–671. New York: John Wiley 1978
Slatko, B.E.: Evidence for newly induced genetic activity responsible for male recombination induction in Drosophila melanogaster. Genetics 90, 105–124 (1978)
Slatko, B.E., Hiraizumi, Y.: Elements causing male crossing over in Drosophila melanogaster. Genetics 81, 313–324 (1975)
Snedecor, G.W., Cochran, W.G.: Statistical Methods, 6th edition. Ames: The Iowa State Univ. Press 1967
Spofford, J.B.: Position-effect variegation in Drosophila. In: The genetics and biology of Drosophila (M. Ashburner and E. Novitski, eds.), vol. 1, pp. 955–1018. New York: Academic Press Inc. 1976
Strobel, E., Dunsmuir, P., Rubin, G.M.: Polymorphisms in the chromosomal locations of elements of the 412, copia, and 297 dispersed repeated gene families in Drosophila. Cell 17, 429–439 (1977)
Sved, J.A.: Hybrid dysgenesis in Drosophila melanogaster: a possible explanation in terms of spatial organisation of chromosomes. Aust. J. biol. Sci. 29, 375–388 (1976)
Sved, J.A.: The ‘hybrid dysgenesis’ syndrome in Drosophila melanogaster. Bioscience 29, 659–664 (1979)
Van't Hof J., Sparrow, A.H.: A relationship between DNA content, nuclear volume, and minimum mitotic cycle time. Proc. nat. Acad. Sci. (Wash.) 49, 897–902 (1963)
Walker, P.M.B., Flamm, W.G., Mclaren, A.: Highly repetitive DNA in rodents. In: Handbook of molecular cytology (A. Lima-de-Faria, ed.), pp. 52–66. Amsterdam: North-Holland Publ. Company 1969
Yamamoto, M., Miklos, G.L.G.: Genetic studies on heterochromatin in Drosophila melanogaster and their implications for the functions of satellite DNA. Chromosoma (Berl.) 66, 71–98 (1978)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sved, J.A., Verlin, D. Similarity of centromeric heterochromatin in strains of Drosophila melanogaster which interact to produce hybrid dysgenesis. Chromosoma 78, 353–363 (1980). https://doi.org/10.1007/BF00327393
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00327393