Summary
Histological material of prostatic carcinoma of 73 patients was reviewed for the purposes of assessing the accuracy and correlation of the initial needle biopsy with the total prostatectomy specimen. Utilizing two prevalent grading systems (Gleason and Gaeta), there was an accuracy of 90% when the two samples graded a well-differentiated carcinoma and an agreement of 70% in the assessment of moderately-differentiated lesions. The use of either system also correlated with the pathological stage of the disease in this group of patients with clinically localized prostate cancer. It is concluded that the prostate needle biopsy is highly representative of the histology of the whole tumor and it has considerable significance in the clinical evaluation of tumor volume in patients with prostate cancer.
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Gaeta, J.F. The accuracy of needle biopsy in the characterization of prostate cancer with the use of gleason and gaeta systems. World J Urol 5, 96–98 (1987). https://doi.org/10.1007/BF00327065
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DOI: https://doi.org/10.1007/BF00327065