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Stage A prostatic cancer: a comparative study in Japan and the Netherlands

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Summary

To obtain more accurate information on the prevalence of stage A prostatic cancer (incidental or latent carcinoma), a prospective collaborative study was set up in Japan and the Netherlands. A total of 859 specimens were submitted for routine histological examination (Japan: 343 specimens; the Netherlands: 516 specimens). All specimens were obtained from patients more than 50 years of age showing clinical signs of obstructive benign prostatic disease. The overall prevalence of stage A cancer in both countries was almost equal (Japan 13% vs the Netherlands 14%). A relatively large number of incidental tumors were found in subcapsular prostatectomy specimens in the Netherlands. Increasing prevalence of stage A disease in subsequent age decades was not found in the Netherlands, where the highest prevalence was observed in the 70–79 age-group. Subdivision of stage A disease into A1 and A2 tumors did not reveal any significant difference in prevalence between the two countries. Of particular interest is that the number of A2 lesions found in the Netherlands was not higher than that found in Japan. In both countries almost all A1 lesions were identified as G1 tumors in stage A1 disease. Both G2 and G3 lesions were present in Japan and the Netherlands in 79% and 72% of the A2 cases respectively. Results are discussed and especially related to their possible impact upon the differences in mortality rate between the two countries.

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Authors and Affiliations

  1. Laboratory of Anatomic Pathology, Kyoto University Hospital, Kyoto, Japan

    H. Yamabe

  2. Department of Pathology, Erasmus University, Rotterdam, The Netherlands

    F. J. W. ten Kate & M. P. W. Gallee

  3. Department of Urology, Erasmus University, Rotterdam, The Netherlands

    F. H. Schroeder

  4. Department of Urology, Faculty of Medicine, Kyoto University, Kyoto, Japan

    K. Oishi, K. Okada & O. Yoshida

Authors
  1. H. Yamabe
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  2. F. J. W. ten Kate
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  3. M. P. W. Gallee
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  4. F. H. Schroeder
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  5. K. Oishi
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  6. K. Okada
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  7. O. Yoshida
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Yamabe, H., ten Kate, F.J.W., Gallee, M.P.W. et al. Stage A prostatic cancer: a comparative study in Japan and the Netherlands. World J Urol 4, 136–140 (1986). https://doi.org/10.1007/BF00327009

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  • DOI: https://doi.org/10.1007/BF00327009

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