Summary
Histologic differentiation, tumor volume and survival rate show that incidental prostatic carcinoma is not a uniform tumor. A retrospective study of 169 consecutive patients with incidental carcinoma was performed; stage and histologic pattern are shown for 135 patients; in 105 patients stage and histologic differentiation pattern are compared to the 5- and 10-year survival rates. In a small series of patients a morphometric analysis was performed to determine the relative and absolute amounts of prostatic carcinoma cells in transurethral prostatic specimens. The histologic pattern in stage A1 (= focal) disease was well differentiated in 62% and moderately differentiated in 38%. Patients with diffuse (= A2) disease showed a well differentiated histologic pattern in only 13%, a moderate differentiated in 35% and a poorly differentiated in 52%. The overall 10-year-survival rate in patients with stage A1 disease was calculated to be 59%, that of stage A2 lesions 40%. Depending upon the histologic pattern in stage A2 patients there is a significant difference in the 10-year-survival rate (A2 G1: 63%, A2 G2: 49%, A2 G3: 28%). Regarding the relative and absolute tumor amounts the morphometric analysis shows as significant difference between A1 and A2 lesions.
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Bartsch, G., Dietze, O., Hohlbrugger, G. et al. Incidental carcinoma of the prostate — Grading and tumor volume in relation to survival rate. World J Urol 1, 24–28 (1983). https://doi.org/10.1007/BF00326858
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DOI: https://doi.org/10.1007/BF00326858