Summary
The authors have reexamined the liver of Myxine with the light and electron microscopes. The observations demonstrate that the liver in this animal is really a tubular gland, in accordance with the conclusions of older anatomists, but in contrast to more recent statements. The existence of a tubular pattern in the liver of the lowest living vertebrate is important for the elaboration of a valid general model of liver structure, which necessarily has to be based on comparative anatomy.
The special cytology of the liver and the ductular cells is presented.
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References
Afzelius, B. A.: The occurrence and structure of microbodies. A comparative study. J. Cell Biol. 26, 835–843 (1965).
Ashworth, C. T., V. A. Stembridge, and E. Sanders: Lipid absorption, transport and hepatic assimilation studied with electron microscopy. Amer. J. Physiol. 198, 1326–1328 (1960).
Bengelsdorp, H., and H. Elias: The structure of the liver of cyclostomata. Chicago Med. School Quart. 12, 6–12 (1950).
Bertolini, B.: The structure of the liver cells during the life cycles of a brook-lamprey (Lampetra zanandreai). Z. Zellforsch. 67, 297–318 (1965).
Braus, H.: Untersuchungen zur vergleichenden Histologie der Leber der Wirbeltiere. Jena. Denkschriften V (Semon, Zoolog. Forschungsreisen II) 4, 303–367 (1896).
Chambers, V. G., and R. S. Weiser: Annulate lamellae in sarcoma I cells. J. Cell Biol. 21, 133–139 (1964).
Cole, F. J.: A monograph on the general morphology of the Myxinoid fishes, based on a study of Myxine. Part V. The anatomy of the gut and its appendages. Trans. roy. Soc. Edinb. 49, part II, 293–344 (1913).
Daems, W. Th.: The micro-anatomy of the smallest biliary pathways in mouse liver tissue. Acta anat. (Basel) 46, 1–24 (1961).
David, H.: Zur submikroskopischen Morphologie intrazellulärer Gallenkapillaren. Acta anat. (Basel) 47, 216–224 (1961).
Elias, H.: A re-examination of the structure of the mammalian liver. I Parenchymal architecture. Amer. J. Anat. 84, 311–334 (1949).
—: Anatomy of the liver. In: C. Rouiller, (ed.), The liver, vol. I, p. 41–59. New York: Academic Press, 1963.
—, and H. Bengelsdorf: The structure of the liver of vertebrates. Acta anat. (Basel) 14, 297–337 (1952).
Farquhar, M. G., and G. E. Palade: Functional complexes in various epithelia. J. Cell Biol. 17, 375–412 (1963).
Gross, B. G.: Annulate lamellae in the axillary apocrine glands of adult man. J. Ultrastruct. Res. 14, 64–73 (1966).
Hering, E.: Über den Bau der Wirbelthierleber. Arch. mikr. Anat. 3, 88–114 (1867).
Holm, J. F.: Über den feineren Bau der Leber bei den niederen Wirbeltieren. Zool. Jb., Abt. Anat. u. Ontog. 10, 277–296 (1897).
Holt, S. J., and R. M. Hicks: Studies on formalin fixation, electron microscopy and cytochemical staining. J. biophys. biochem. Cytol. 11, 31–46 (1961).
Karnovsky, M. J.: Simple methods for “staining” with lead at high pH in electron microscopy. J. biophys. biochem. Cytol. 11, 729–732 (1961).
Low, F. N.: A boundary membrane concept of ultrastructure applicable to the total organism. In: Electron microscopy, p. 115–116. Proceedings of the third European Regional Conf., Prague 1964, ed. by M. Titlbach. Prague: Publ. House of the Czechoslovak Academy of Sciences 1964.
Marinozzi, V., et W. Bernhard: Présence dans le nucléole de deux types de ribonucléoprotéines morphologiquement distinctes. Exp. Cell Res. 32, 595–598 (1963).
Mazzanti, L., e E. Mugnaini: Quadri elettron microscopici di epatociti di ratti alimentati con una dieta ipoproteica, iperlipidica e iperglucidioa. Atti del III Congr. Ital. di Microscopia elettronica, p. 123–128. Milano: Fondazione Carlo Erba, 1961.
Millonig, G.: Advantages of a phosphate-buffer for osmiumtetroxide solutions in fixation. J. appl. Phys. 32, 1637 (1961).
Mugnaini, E.: Studio ultrastrutturale sul fegato grasso da pasto lipidico. Thesis University of Pisa, Italy, 1962.
—: Filamentous inclusions in the matrix of mitochondria from human livers. J. Ultrastruct. Res. 11, 525–544 (1964).
- Unpublished observations 1966.
Palade, G. E., and C. Schildowsky: Functional association of mitochondria and lipide inclusions. Anat. Rec. 130, 352–353 (1958).
Penn, R. D.: Ionic communication between liver cells. J. Cell Biol. 29, 171–173 (1966).
Retzius, G.: Weiteres über die Gallenkapillaren und den Drüsenbau der Leber. Biol. Unter-suchungen, N. F., 11, 67–70 (1892).
Roullier, C., and A. M. Jézéquel: Electron microscopy of the liver. In: C. Rouiller (ed.), The liver, vol. I, p. 195–264. New York: Academic Press, 1963.
Sanders, E., and C. T. Ashworth: A study of particulate intestinal absorption and hepatocellular uptake — use of latex particles. Exp. Cell Res. 22, 137–145 (1961).
Sommerfelt, L.: Untersuchungen über den Bau der Leber bei niederen Wirbeltieren. Anat. Hefte 55, 665–769 (1918).
Yamamoto, T.: Some observations on the fine structure of the terminal biliary passages in the goldfish liver. Anat. Rec. 142, 293 (1962).
—: Some observations on the fine structure of the intrahepatic biliary passages in goldfish (Carassius auratus). Z. Zellforsch. 65, 319–330 (1965).
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Mugnaini, E., Harboe, S.B. The Liver of Myxine glutinosa: A true tubular gland. Z. Zellforsch. 78, 341–369 (1967). https://doi.org/10.1007/BF00325318
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DOI: https://doi.org/10.1007/BF00325318